Thursday, August 30, 2007

Discovering the enzyme which changes the B type blood into O type

A, discovering the enzyme which changes the B type blood into O type


 In only the person of the same type of blood the method of changing into the O type which can be transfused by anyone was discovered the blood of A type and the B type which cannot be transfused. If safety and effectiveness of this method are verified, insufficiency of the blood for transfusion can think also that it becomes past ones, expectation and interest are moved aside. This knowledge was published to scientific magazine “Nature Biotechnology” April 1st online edition.

 Most people, have either inside four types of blood A, B, O or AB. At cell level, there is the respective individual sugar molecule on the surface of the red corpuscle of A type and B type, with AB type the both sugar molecule of A and B exists. For example when the blood of A type you transfuse to the person of B type, this sugar molecule becomes “the antigen”, induces the fatal immune reaction. However, in the circumstance of the emergency which does not have the room which as for the blood of O type because it does not have this “antigen”, it can use safely by anyone, the type of blood of the especially patient inspects it is useful. Because of this, if the blood of O type is used and more than other type mentions “blood insufficiency” you say that it means to mean the insufficiency of O type.

 In order to cancel this insufficiency, removing the antigen of A type and B type from the red corpuscle, the technology which it changes into O type becomes necessary. If the enzyme is used, it was thought that it is possible, but those where the enzyme which designates just the antigen of A type and B type as the target is discovered were difficult problem. Test was executed in the past, the American ZymeQuest corporation (Massachusetts state) concerning the enzyme which was refined, if, but the antigen remains even from 1%, it was found that the immune reaction occurs, the good result was not obtained.

 Two bacterial enzyme families which are called the glycosidase where in the latest research, the team of Henrik Clausen doctors of the 0 0N Harvard University medical department and the Copenhagen university, inspects the database of the bacterium and Eumycetes thoroughly, can remove this sugar molecule as the target were discovered.

 The american blood center (ABC) Louis M. Katz doctor concerning this enzyme “has the necessity to advance regardless to clinical test”, that although it does that several doubt remains, you express, you point out the possibility the little residue of possibility and the enzyme itself where the immune reaction happens the enzyme vis-a-vis the red corpuscle which was processed causing immunity obstacle. In addition, Katz touches concerning the problem of cost, when the one which applies the fund which is necessary for the enlargement of this kind of technology, to the collection of the blood donor is good, it has expressed also viewpoint. Presently, every year 5% of population has donated blood, but if this becomes 7%, blood insufficient problem when it is the expectation which is cancelled Katz has expressed.

Asthmatic risk increases with weight increase

Asthmatic risk increases with weight increase


 As for passing weight and the person of obesity, it made the asthma clear in comparison with the person of standard weight, was published to the medical magazine “American Journal of Respiratory and Critical Care Medicine” April edition that it is easy to emerge. The research group when tackling asthmatic management, has expressed that it is necessary to keep seriously considering proper weight management.

 The American stand hygienic laboratory (NIH) according to, as for the asthma in the inflammation of the windpipe and the chronic disease which accompanies strangulation, as for healing it is difficult, but there is many a thing whose management is possible. Repeatability ringing , (the weir), there to be a condition such that it is easy to cause the allergy, the number of affection in the United States people includes child patient 9,000,000 and is called approximately 2,000 ten thousand people. According to recent investigation, obesity or it passes American 65% and it assumed that it is weight, also connection of the asthma and obesity was shown in former research.

 In the latest research, the American stand Judean medical research center (Denver) E. Rand Sutherland doctors, in 1966~2006 year above the total 330,000 3,000 people targeting examined the data of 7 research which were inspected BMI (obesity exponent) with concerning the asthma in the United States, Canada and Europe. It hit to the review, under BMI25 “standard weight”, “passed it adopted the 25~29 and, weight” and the standard scale which makes 30 or more “becoming fat”. As a result, BMI as for the person of 25 or more asthmatic emergence ratio 50% is high, weight increases following and you say that also risk increasing was ascertained. As a result man and woman difference was not recognized.

 The research group have assumed that passing weight dangerous factor (the risk factor) with has the necessity to add the asthma to one of the disease which becomes, on the basis of this knowledge. When obesity or it passes and thinks of the population of the weight person, as for American who has asthmatic risk rather than being thought so far, several 1,000,000 people mean many thing, but you say that there is also a possibility where annual 250,000 can decrease the asthmatic patient with “substantial loss in quantity” on the one hand. But, unless it passes and there is no disease depending upon weight, because decrease of lung capacity and restraint of the breast-wall is pulled up, there being a breathing apparatus condition, always, the asthma it limits, the specialist has expressed.

 Another specialist in former research lists the fact that it is not made clear concerning man and woman difference, the latest research has expressed at this point in time that it is interesting. It is difficult to make the causal relation clear, whether the asthma of the not yet diagnosis which is from or the time before where obesity really becomes cause of the asthma with obesity increase badness it does but obscurity, that obesity is dangerous factor of the grave asthma, we have assumed that you are not wrong.

The vegetable and the fruit repulse the cancer (the cancer)

The vegetable and the fruit repulse the cancer (the cancer)


 By the intake of the vegetable and the fruit, the various cancer (the cancer) three research which show the fact that risk decreases, the American cancer academic society which is held in Los Angeles (AACR) were reported with annual meeting.

 The american stand cancer laboratory (NCI) as for the research by Neal Freedman, targeting adult 490,802, the intake quantity of the fruit and the vegetable and those which compare the rate of occurrence of the head neck cancer. The fact that it was diagnosed the head neck cancer in 5 years was 787. Smoking and alcoholic intake dangerous factor (the risk factor) after the adjusting, concerning 1 day 1,000 caloric intake such as fruit or as for the person who 6 plates takes in the vegetable, head neck cancer risk 29% was low only 1.5 plates in comparison with the person who is not taken in, 1 plates just adds even could recognize 6% risk decrease. Independently you say that you could see the preventive effect where the vegetable is higher than the fruit.

 The american University of California Los Angeles (UCLA) the research group the broccoli and the soybean (the soy bean) the protein (the protein) due to reported the research result at laboratory level concerning the mechanism of the preventive effect for the breast cancer and the ovarian cancer. When the broccoli is digested, when [jiindorirumetan] (DIM) with the substance which is said is digested, the soybean, the substance, [genisutein] is formed. This time, these substances, operated the maneuverability of the cell of the breast cancer and the ovarian cancer, it was found that spread of the cancer is controlled. But, in the soybean the estrogen way because there is action, the person who has the cancer which is promoted by the estrogen says that note is necessary.

 The research group of American Hawaiian cancer research center targeting 180,000 3,518 people of California and the Hawaiian residence compared the intake quantity and cancer risk. As for, the onion and the apple, the substance which very is included in type, the kale and the broccoli etc. Besides the fact that with the person where the intake quantity is highest cancer risk 23% low thing it was understood, with the smoker furthermore the effect is large, as for the person where the intake quantity is high cancer risk was ascertained 59% low thing.

 When you can say, that it is best to cancer prevention to take in the plant characteristic food of various types from 3 research above, the American cancer research association (AICR) Melanie Polk has expressed. Besides the fact that it goes to the direct sales depot of the farmer, spends time at the foodstuff store and closely examines the vegetable, when also the device such that the cooking method which can eat the vegetable tastily is found it is necessary Polk calls.

Wednesday, August 29, 2007

Controlling the hyperhidrosis with sympathetic nervous amputation

Controlling the hyperhidrosis with sympathetic nervous amputation


 The surgical operation which cuts off the nerve which stimulates the sweat gland of the skin, was shown in the research whose it is new to be useful in hyperhidrosis remedy.

 The hyperhidrosis patient who is troubled to the excessive sweat says that approximately 100,000,000 9,700 ten thousand people who hit to 3% of worldwide population it exists. You can see the sweat of the usual 3~4 time quantity, the palm and the armpit (side) under, condition appears mainly in the face and the foot etc. Accurate cause is not recognized, but it is assumed that it occurs due to the fact that the nerve which stimulates the sweat gland operates excess. In cure, section and the medicine medical therapy due to orally, other than the [bototsukusu] injection and ion introduction etc, when you cannot see the effect with this kind of remedy, there are also choices, surgical operation.

 The american Barrow [baro] nervous study laboratory (BNI, Arizonan state) in the latest research by the team, lapse 300 of hyperhidrosis patients who receive the pleural cavity Kiyouka sympathetic nervous excision technique both sides was inspected. Being something where, this operation inserts the small-sized fiber camera and the operation instrument from the small incision section of 3 places, cuts off the nerve which becomes cause of the multi sweats, quite invasive characteristic is low. As for the inside 129 people of the subject as for the palm and 11 people as for the armpit and 160 people it was the patient where both of the palm and the armpit you can see the excessive sweat.

 By this operation, the hyperhidrosis of the palm was settled with 99.3% of the patients, the hyperhidrosis of the armpit was settled with 61%. As a complication, 2 examples of the arrhythmia and 1 examples of the melancholia after the technique, the pneumothorax after the technique (the sick condition where the air accumulates in the pleural cavity) it could recognize 9 examples, these inside 5 examples required [dorenaji] by the pleural cavity tube. For pleurum adhesion the patient who preventively requires pleural cavity [dorenaji] was 4 examples.

 In addition, besides the fact that the chest, it could recognize in another region the compensation characteristic hyperhidrosis which such as back and leg the multi sweats occur as 16 examples, mistaking as 7 examples, you could see the [horuneru] syndrome due to damaging the nerve. In [horuneru] syndrome, the sweat and the eyelid of the face (the eyelid) you can see hanging down and the pupil reduction etc the side which is the nervous damage. Furthermore, as 6 examples intercostal (the [ro] [tsu] can) intercostal by the damage of the nerve it was recognized neuralgia.

 This research the American cranial nerve surgical academic society which is held with Washington D.C. (AANS) was announced with annual meeting.

Influence of the insomnia is larger in night oak family

Influence of the insomnia is larger in night oak family


 Influence of the insomnia seems that differs depending upon the sleep habit of that person. As for “night oak family”, from the person who likes going to bed early the body and mental pain which the insomnia brings became large, in addition, entire sleep time relatively is many the stress for the insomnia in spite, being strong in the American research clear.

 American Stanford University (California state) Jason C of the sleep obstacle clinic. as for Ong, 312 outpatients who start group conduct medical therapy with the same clinic to 1999~2004 year (as for the inside woman) targeting 60%, before becoming the insomnia, you inquired about the taste of sleep schedule, classified into the “early rising group”, the “night oak group” and the “intermediate group”. After that, curfew period, frequency of awakening, quality of time and the sleep which occurred in the sleep time zone, all the sleep times, examining the sleep diary which 1 weeks records the hypnotics which are taken. Furthermore, the [u], consecutive psychology measurement such as frustration, the insomnia and examination of the negative thought for all sleep it did.

 As a result, as for the night oak group, by comparison with the early rising group and the intermediate group, in the sleep time zone it is not in the bed the time when long, from feels lack of sleep what became clear. In addition, there is no coherence in going to bed rising habit, the [u] due to the insomnia feeling and stress were strong. As for the night oak group, influence of the insomnia and because sleep cannot be controlled, the fact that you sleep mainly was selected, result sleep time had become long. With quality of frequency of awakening and use and sleep of the sleeping pill, as for the difference it was not recognized between the groups. This tendency was the same with the man and woman.

 As for Ong, sleep schedule of the individuals is related to each insomnia, but we have assumed that the latest knowledge is not the case that the respective causal relation clear it is done, only connection of the taste and the insomnia of sleep time just was shown. In research, as for density in the blood of [koruchizoru] and the melatonin and fluctuation etc of the body temperature which is in the midst of sleeping we were not measured, also the diseased patient who exerts influence on sleep pattern was included. However, considering such point, the same person ““is connected to the remedy which the research result adjusts to patient peculiar insomnia profile””, that it has done.

 The person whom the American Rochester university (New York) Michael L of sleep Director of Laboratories. as for Perlis although “the entrance sleeping difficult person is, the person whose sleep maintenance is difficult and early the person of awakening, furthermore those unite and are brought together it is. Cause of the insomnia is made clear, compared to knowing the disease, is connected to the development of a better cure”, that you have expressed.

 The research result was published to the American medical magazine “Journal of Clinical Sleep Medicine” April 15th number.

The one headache which is in the midst of becoming pregnant the heart disease, is related to stroke

The one headache which is in the midst of becoming pregnant the heart disease, is related to stroke


 While becoming pregnant as for the woman who has one headache, the research which shows the fact that the possibility blood vessel obstacle of stroke and the heart seizure etc occurring is high significantly, the American nervous academic society which is held in Boston (AAN) was announced with annual meeting.

 The american duke university (North Carolina) Cheryl Bushnell doctors of medical center assistant professor examined the data which is in the midst of woman approximately 1,700 ten thousand becoming pregnant from 2000 extending through 2003. Approximately 30,000 4,000 person among these has received the remedy of one headache, while becoming pregnant as for the woman who has one headache, stroke risk 19 times, heart seizure risk 5 times, other blood vessel obstacle risks such as the heart disease and the thrombus being 2 times or more it was understood. In addition, as for the woman where age when giving birth is 35 years old or more, while becoming pregnant the probability where you can see one headache was high.

 As for Bushnell doctor, it is not the case that it can support the causal relation with this, it is necessary further in the future to repeat research, but one headache and blood vessel dangerous factor (the risk factor) as for the woman whom it has simultaneously, while becoming pregnant you have expressed that it is necessary to endeavor to the improvement of dangerous factor.

 American Montefiore [montehuiori] headache center (New York city) Richard Lipton doctor have assumed that it is necessary to consider one headache similar to diabetes and high cholesterol, as those which it should manage. As for the person who has one headache, simply insecurity is not [ru], appropriate remedy is received, doing, you say that the heart disease and managing the dangerous factor of stroke are important, e.g., weight and the blood pressure are maintained properly.

 In past research, besides the fact that the one headache which is in the midst of becoming pregnant becomes dangerous factor of stroke, it is found, that it becomes also estimate factor of the heart disease, between the one headache and relation of stroke and the heart disease is recognized even with the woman who does not become pregnant. When it is the heart disease and dangerous factor of stroke, when also evidence is shown large number, Lipton you express the one headache which accompanies especially omen.

 As for one headache from the fact that it is blood vessel characteristic headache, when even biologically it has served to reason, Bushnell has expressed the latest knowledge. But, you say that it is problem the person who has one headache specifies no 100,000 person while being, the person who has risk how that. Confronting, when already diabetes, the person who has dangerous factor such as hypertension and obesity, should think with the woman who makes pregnancy the tip extending that this information was obtained with good timing, the same person has expressed.

With excess intake of multiple vitamin prostate cancer (cancer) risk increase

With excess intake of multiple vitamin prostate cancer (cancer) risk increase


 When the multiple vitamin is taken in excessively, the report that, the American stand cancer laboratory (NCI) was published to the medical magazine “Journal of the National Cancer Institute” May 16th number of issue the prostate cancer of the man (the cancer) risk increases.

 Exceeding week 7 time, when it takes in the multiple vitamin, risk of the advance prostate cancer 32% increases in comparison with the man whom it does not take in completely, as for the death risk due to the prostate cancer says that it reaches approximately 2 times. The relationship of this, the man and the selenium which have the family history of the prostate cancer, especially was strongly seen the supplement of the microelement (the nutrition auxiliary food) in the man who such as beta carotin has taken in individually and zinc.

 Those where Michael F of NCI. the man approximately 300,000 person it had entering the latest research where Leitzmann doctors do, in the questionnaire targeting, past concerning the multiple vitamin intake of 12 months, after that the subject 6 years pursued cancer the whole prostate gland and heavily seriously concerning the emergence of the prostate cancer of type they inspected. When it takes in excessively to which, whether risk increases it is not made clear, Leitzmann, has expressed that in this kind of epidemiology research it is difficult to remove the other factor which is related to the use of the multiple vitamin.

 With the discourse which is published to the same number, it was pointed out, that it has the anti- oxidation action whose many of the supplement are strong besides the fact that the doubt for the profit of the anti- oxidation vitamin medicine with the latest research furthermore became deep, it is assumed that also the possibility of bringing the result which the anti- oxidation supplement expects the person healthily became relief. However as for NIC, as for the schedule which advises anew concerning the use of the multiple vitamin you say that it is not. 

 The latest result the American cancer association (ACS) agrees with the result of the large-scale research which is executed 2 years ago. As for this research being something which 18 years man approximately 500,000 people is pursued, the mortality rate due to the prostate cancer of the man who takes in the multiple vitamin of month 15 time or more is shown, barely being higher than the man who is not taken in. Also both research about the man who takes in the supplement mainly risk is large, view is similar entirely”, that Victoria Steven it does has expressed this research.

 According to Steven, as for society being negative already, with standard guide as for use of the multiple vitamin it is not recommended vis-a-vis the multiple vitamin. But as for the vitamins taking in from the natural food the best, when the person where it is necessary to take in the vitamin medicine the pregnant woman as beginning the BASIC where balance comes off should use the [maruchibitamin] supplement the same person has expressed.

It is low in the person where the insulin secretion quantity is many carbohydrate diet

It is low in the person where the insulin secretion quantity is many carbohydrate diet


 The person where the insulin secretion quantity is many, rather than taking in the meal of the fat and the high carbohydrate low, fat amount being a little overplentiful, was shown in the research whose it is new, for the method which takes in the meal where the refining carbohydrates are few to be easier to decrease weight was published to the American doctor periodical “JAMA” May 16th number.

 As for Cara Ebbeling of the American Boston child hospital, effective meal plan differs depending upon the difference of the insulin secretion quantity, whether or not, is you paid attention, the young adult of obesity (the 18~35 year) targeting 73 people pursuit of remedy period of 6 months and follow-up period of 12 months you did. So far, low that success or failure of the diet by the fat food divides it assumed that simply it is problem of desire, but when from the latest result, at least you can think the difference of the insulin secretion one of cause, Ebbeling has expressed.

 In the latest research, the half of the subject carbohydrate 55%, took in the meal of fat 20%, the remaining half carbohydrate 40%, took in the meal of fat 35%. When starting the research, after taking in dextroglucose 75g orally, insulin density in the blood was measured. Altogether as for difference of weight decrease it was not seen between both groups, but although low with the fat food 2.6 pounds (approximately 1.2kg) was in 18 months, you compared the weight decrease of the person where insulin value exceeds average, low with the carbohydrate food 12.8 pounds (approximately 5.8kg) with there was a big difference in 18 months. In addition, low with the carbohydrate food group HDL (the virtue ball) cholesterol and triglyceride (the neutral fat) vis-a-vis value improving largely, LDL (the bad character) concerning cholesterol you say that big improvement it could recognize the fat food low.

 With the person where past you cannot see the loss in quantity effect low with the fat food, when low there is a possibility the blood glucose load food being effective, as for Ebbeling you have expressed. It is low, as for the blood glucose load food the blood glucose index (GI) being something which centers the low carbohydrate, absorption being lenient, it is possible to maintain insulin value relatively at stability. Low to make the blood glucose load food, the milling pan, the milling grain cereals, the cookie and the sweet beverage etc you avoid, you say that the fruit, the vegetable and the beans, low it is good to take in the milling grain cereals mainly.

 The american nutrition association (ADA) Lona Sandon has expressed that it could support the fact that the specialist feels so far vaguely, with this research. But, many people not to have grasped their own insulin secretion quantity and the like, because it is obesity, saying, unless it is the case that always insulin value is high the same person points out. If by Ebbeling, for you to inform your own insulin production quantity, when oral dextroglucose load test should have been taken, is.

The reaction of the doctors is calm in heart diseased risk of the diabetes medicine

The reaction of the doctors is calm in heart diseased risk of the diabetes medicine


 The diabetes remedy Avandia which is used widely as an insulin resistant improvement medicine (general name: Although in the news that, the medical specialists have shown anxiety, in rosiglitazone, & the Japanese country not yet approval) makes heart seizure risk increase, the reaction which settles generally is shown. But this knowledge, those which are published to the American medical magazine “New England Journal of Medicine” June 14th number, the importance with respect to public health the empty same magazine published on May 21st.

 The american diabetes association (ADA) the Sue Kirkman doctors specialist become in panic, vis-a-vis the patient, consulting the family doctor, judges, whether or not risk exceeds the profit, that the medicine is not discontinued selfishly, has advised. The discourse that was published to the English medical magazine “Lancet” May 26th number, it should examine calmly, concerning the safety of Avandia.

The american food medical supply bureau (FDA) the latest knowledge was received, warning regarding the safety of Avandia was sent, but concerning the alarm display to the label you waived furthermore examination as necessity. According to AP communication, the result which supports the latest knowledge even in the spare research which FDA executes individually is shown, the FDA inquiry members are warning which is strongest concerning Avandia several months ago, Charles Grassley Senator (the Republican Party, Iowa state) pointing out that indication of “black box warning” is advised. As for FDA although indication Grassley was recognized, there is also a data which is contrary, you have expressed that it is in the midst of examining.

 As for executing the latest research Steven E of the American Cleveland clinic. Nissen doctor and Kathy Wolski. Nissen doctor past as Avandia besides the fact that the heart diseased risk by the medicine muraglitazar of the same class was made clear, assuming that the arthritis remedy (the COX-2 obstruction medicine) Vioxx makes increase the heart seizure and stroke risk to 2004, has driven to the sale discontinuance. In the latest research, as for the patient who uses result and Avandia which are appraised the patient who uses Andiva concerning 42 research which compare with the patient who has not been used heart seizure risk 43% is high, calls the death risk due to the heart blood vessel disease that 64% high thing was ascertained.

 The production original [gurakuso] [sumisukurain] corporation of Avandia when it is based on basis and the procedure where the latest research is imperfect is strong refutation. Avandia is used 2,000,000 person or more in the world since approving 1999, as 2 type diabetes medicines, annual 3,200,000,000 dollar (approximately 3,800 hundred million Yen) is a sale. You say that from the fact that it is effective to the fundamental problem of the diabetes, insulin resistance, there is a possibility in the future widely of keeping being used.

Original

Surgical operation is effective to the pain of the back

Surgical operation is effective to the pain of the back


 The slipped disk and due to the sciatic nerve painfully pain of the back and the leg it is eased quickly, surgical operation being effective, whether or not naturally it heals, in order to see circumstances, extending the time of operation first, to the effect of operation as for difference it is not due to 2 research that the knowledge, was published to the American medical magazine “New England Journal of Medicine” May 31st number.

 First research the grave sciatic nerve painfully pain of the leg due to the pressure of the sciatic nerve () those which deal with patient 283 above the 6~12 week it continues. Of the subject early operation (average 2.2 weeks), retention remedy (remedy other than surgical operating) it allotted to the remaining half half from start of research. 39% of the retention remedy groups received operation finally, (operation time from start of research average 18.7 weeks). In the aspect of body ability as for big difference it was not seen in both groups, but if early with the operation group pain is eased quickly and operation is quick, it became clear also for recovery to be quick.

 After as for Wilco Peul doctor of Holland and the Leiden Leyden university medical center which execute research, as for 3~6 mosquito month seeing circumstances from emergence you recommend that it decides operation, but case and the like there is a hindrance in life depending upon pain, also being effective, early to receive operation, according to need you have expressed that they are the safe choices.

 Already as for research of one side, senior citizen and 600 patients of the denaturation vertebral slide symptom which is mainly seen in the black woman being something which strongly is made the object, the American Dartmouth Dartmouth medical science university (new hampshire) James N. Weinstein went. Of the subject surgical operation (vertebral fixed technique), remaining standard non surgical remedy was allotted half mainly half randomly, but because many of the non surgical remedy group receive operation afterwards, adjustment of the data was required. Of 3 months later and at point in time of 1 years later, among the surgical remedy group pains were few in comparison with the non surgical remedy group, could see substantial improvement even in the functional aspect.

 According to Jeffrey Spivak of American New York university hospital joint diseased vertebral center, is not the case that, always operation is suited for any pain, but you say that with case of part pain can be eased quickly by operation, can expect that also recovery of function is hasty. The latest 2 research, when effectiveness of surgical operation is supported, simultaneously, postponing operation, have shown the fact that it is not the case that the effect goes down, when it becomes help of the cure selection which is suited for the patient the same person has expressed. As for another specialist, the back section there is various primary factors painfully, to receive the remedy which is suited for condition, in order to receive the medical examination of the specialist who becomes skillful as much as possible you recommend.

Breast cancer (cancer) radiotherapy period shortening possibly

Breast cancer (cancer) radiotherapy period shortening possibly


 When the strength irregularity radiotherapy which applies radiation to the target accurately (IMRT) with utilization, the exposure per 1 days is increased, the breast cancer (the cancer) remedy period of the patient from the former 6~7 week can be shortened in the only 4 weeks, the research result, was published to the medical magazine “International Journal of Radiation Oncology Biology Physics” June 1st number.

 The american Fox Chase fox chase cancer center which does (Philadelphia) according to Gray Freedman doctor, with the breast cancer patient where the tumor is small at least, with combined use of tumor extraction technique and radiotherapy, being able to obtain survival ratio and the healing ratio which are equal to breast excision technique has been supported report sufficiently. But, the woman who steps on two feet from the fact that the 6~7 week is required is many in radiotherapy, shortening in period has become important topic. In several research, it is examined concerning the lighting from outside the body and the remedy of 1 weeks which jointly use the pad of the radioactivity seed, but this remedy is suited for only the patient of the extremely part where the tumor quite is small.

 In the latest research, the remedy where the dose per 1 days is higher than the normality 75 women of the breast cancer making use of IMRT targeting (the even 52 years old), was executed, the side effect was inspected. With until recently you say that it is not the case that total of the dose becomes many, in comparison with this 4 weekly remedy it is 56Gy meter 60Gy (the unit which shows Gray and the absorbed dose) vis-a-vis irradiating with remedy of the usual 6~7 week. With IMRT, quite be able to irradiate radiation to the specific region inside the tumor or the tumor accurately making use of the X-ray accelerator which the computer controls, it is possible to leave being bombed of peripheral organization in minimum.

 As for the result of short term being satisfactory, as for the side effect which exceeds former remedy it has not come out. It could recognize skin obstacle in the patient of part, but it was settled to 6th week, appearance of the skin returned 6 weeks later, similarly to before the remedying from remedy end. In order in the future, to verify the presence of long-term problem, pursuit of 5 year is done. From past research, it is found that heart diseased risk of the woman who receives radiotherapy to the eighties is high, but if IMRT is used, being bombed of the heart decreases, says that it is the expectation which can lighten also risk. 

 However, also Freedman has recognized the fact that it is the fault that the facility which can be utilized is limited to IMRT. In addition, the latest research being small-scale, also the point where doubt remains furthermore the point where it has the necessity to verify and, long-term concerning the possibility of virulence and recurrence is pointed out from the other specialist.

Liver cancer (cancer) in remedy big advance

Liver cancer (cancer) in remedy big advance


 Molecular target medicine sorafenib [sorahuenibu] (trade name: When Nexavar, the Bayer corporation, * in the Japanese country during application approval applying of the kidney cell cancer), the advance liver (the cell) you can see the effect where is high to the cancer, the result of clinical test SHARP trial, the American cancer remedy academic society which is held in Chicago (ASCO) was announced with annual meeting. When the same medicine to the advance liver cancer patient is prescribed, you say that lifetime 44% extended in comparison with the patient who is not prescribed.

 Research the American [mauntosainai] medical science university which does (New York) according to Joseph Llovet doctor, as for the systemic remedy which extends the lifetime of the liver cancer patient you say that this is unprecedented. Passing the randomization engine bench test which exceeds 100 with the research which spans 30, it means that those which should become new standard remedy of the liver cancer patient finally appear. You have expressed that the American cancer association (ACS) Len Lichtenfeld doctor, this remedy probably will change the standard of medical care.

 As for the liver cancer at 3rd rank of cause of the death with the cancer of the world, the case which from diagnosis dies within 1 years it is many. 40% of the liver cancer (Asia and Sahara from here in Africa south 80%), it is diagnosed at the stage which was advanced. Surgical operation and radiotherapy and chemotherapy are done, but the systemic remedy which is by the medicine (the remedy which inserts the medicine in the blood style) so far it did not exist, standard cure was not established. sorafenib with the medicine of tablet type, in the United States is approved already as the advance kidney cancer remedy, (* the possibility that application to the liver cancer is approved during June). In the meeting, the test result to several cancer was announced other than the same medicine.

 In the latest research, 1 day 2 time dosage group and [purasebo] of sorafenib 400mg (the false medicine) to allot 602 advance liver cancer patients, to the group randomly, 6 monthly dosages. As for the [purasebo] group until 7.9 months, the cancer advances, period, with the sorafenib group 5.5 months, with the [purasebo] group they were 2.8 months lifetime of the sorafenib group (median) vis-a-vis being 10.7 months. Quite, you could obtain the satisfactory result, test early ended. As for the side effect you say that it was same with both groups.

 In the meeting, when the colon which has liver transfer (the colon) with the rectum cancer patient, combined use chemotherapy (FOLFOX4) it executes on operation front and back recurrence risk of the liver tumor 30% was shown also the fact that it decreases. The Ambroise Pare hospital which does (Paris) Bernard Nordlinger doctor has expressed research that it becomes the standard remedy where is new with the colon rectum cancer patient where this method has liver transfer. Presently, annual 1,000,000 is diagnosed the colon rectum cancer, can see liver transfer half. Removing the liver tumor with operation, 5 annual survival ratio has been restricted to the 30~35%.

Mismatch of the opinion that the doctor the cancer (the cancer) raises the death risk of the patient

Mismatch of the opinion that the doctor the cancer (the cancer) raises the death risk of the patient


 When it has the opinion which differs from charge medicine the advance cancer (the cancer) the patient concerning itself body state and nutrition state, it was shown in the research death risk becoming high by Ian Schnadig doctors of the American Oregon Health Sciences University cancer laboratory, the American cancer remedy academic society which is held in Chicago (ASCO) it was announced with annual meeting.

 In the latest research, PS of patient (performance status; When the index which shows the systemic health state of the patient and the ability to operate every day) appraisal does not match the doctor, death risk increased 11%, when appraisal of nutrition state does not agree, you say that 38% increasing was ascertained. If appraisal agrees, is not something where, lifetime extends, but when it is thought that lack of communication has brought the deterioration of convalescence, the specialist points out.

 At the time of this research, the team of the same university the advance colon (the colon) obtaining the cooperation of rectum cancer and 1,636 lung cancer patients, executed the pursuit of 7 years. The doctor and the patient were recognized respectively, PS appraisal of 2 types and nutrition state appraisal of 1 types the result of doing, respectively 56.6%, 67.1% and 58%, in each case doing the appraisal where the patient above the half differs from the doctor.

 As a whole, the doctor there was a tendency which acquires the appraisal which is higher than the patient. In addition, with the patient whom it becomes impossible to work before the especially retirement age, the mismatch with the doctor is easy occurring concerning the appraisal regarding work it was recognized. Educational background as for the person under high soldier/finishing besides the fact that you could see the mismatch with the doctor more than the person who has the educational background above the university, frequently the [u] the person who appeals state mismatch ratio was high.

 Schnadig has expressed that it is important to keep agreeing the appraisal that the doctor and the patient, concerning PS and nutrition state. As a method for that, when periodically vital sign of the blood pressure and heart rate etc (life sign) it measures, in the same way, in every fixed period you take the data from the patient and you can think that among other things the appraisal value which is used with thing and the clinical test where makes submit to the doctor is adopted. But, when the doctor should hear the story of the patient better, as simpler solution than that, there is also opinion. “The patient has wished to know his own state”, that the specialist points out.

Heart diseased death risk redoubles even with pre- diabetes

Heart diseased death risk redoubles even with pre- diabetes


 There just is an extremely early sign of diabetes the death risk due to the heart disease increasing, was shown in the Australian research. Still, it is not diagnosed diabetes and the [te], the person where the complication is exposed dangerously large number means to exist.

 In the United States approximately 2,000 ten thousand people have contracted a disease in 2 type diabetes, you say that 6,000,000 person does not become aware in the. 5,600 ten thousand people or more “pre- diabetes (pre-diabetes: The symptom before the diabetes)” with there is a stage which is called, healthy state and the resistance sugar talent abnormality which hits to the center of diabetes (IGT) it has. When 2 type diabetes do not produce the insulin where the body is sufficient, or or when the cell has not reacted to the insulin, this state continues, obstacle happens even to the eye, the kidney, the nerve and the heart. Diabetes is well known heart blood vessel diseased risk and as for early making death risk increase, but relationship between minor blood glucose value rise and heart blood vessel diseased risk was not made so far clear.

 As for the latest research which is reported with the American medical magazine “Circulation” June 19th number, the international diabetes laboratory (Melbourne) those by Elizabeth Bar. As for the research group, the Australian “diabetes, obesity and life habit research (AusDiab)” 10,429 person who participated 5 annual pursuit. Oral resistance sugar talent test of the full participant was executed when starting the test, cholesterol value, triglyceride (TG) value was measured. 5 years later, the person of diabetes 2.6 times that of the person where the risk which dies with the heart disease is healthy, the person who the hungry time is abnormal in blood glucose value (makes “pre- diabetes”) with to be 2.5 times, the person who is diabetes and pre- diabetes 2/3 of the whole death in the heart disease had occupied.

 The specialists interpret this knowledge as quite the important alarm bell. Being something where the latest research furthermore supports the past research result strongly, you insert power above so far in management of dangerous factor of the blood vessel disease, the opinion that and, simply the person just of resistance sugar talent abnormality, it is necessary to promote motion and appropriate dietary life it is necessary to recognize the importance of diabetes as a dangerous factor more strongly, and so on opinion is put out.

 But, how it remedies pre- diabetes, the point in addition whether or not it should remedy of, has not become clear. As for the latest research because it is not something which pays attention to remedy, at least, there are times when it returns to the same as the person whose heart diseased risk of the pre- diabetes patient is healthy from this research, whether or not is, there is also the opinion that it is not understood.

In usefulness of blood glucose self measurement with home question mark

In usefulness of blood glucose self measurement with home question mark


 The english research which shows the fact that blood glucose self measurement with home that much is not useful in remedy of 2 type diabetes, the English doctor periodical “British Medical Journal (BMJ)” June 25th was published by online edition, the American diabetes association which is held simultaneously in Chicago (ADA) was announced even with annual meeting. However, as for this knowledge you say that it is not applicable to the necessary 2 type diabetes patients of insulin remedy.

 Whether or not as for the latest research by Andrew Farmer doctors of the English Oxford University lecturer, for 2 type diabetes patients who do not use the insulin, monitoring of blood glucose value the usefulness those which were examined. The group and the doctor who show affirmative attitude concerning the self measurement of blood glucose value it is, but because cost increases, you say that there is also an insurance company which shows disapproval. “The basis that it was not found self measurement with home makes the management of blood glucose value improve,”, that Farmer has expressed.

 Farmer allotted 453 2 type diabetes patients to 3 groups randomly. As for the 1st group the group which receives the blood glucose measurement of month 3 time. In the 2nd group, to measure at the home due to the measurement equipment, way the result is made to see to the doctor the indication. As oneself it measures with a measurement equipment, the viewpoint of numerical value was guided to the 3rd group.

 Difference of blood glucose value is not recognized 1 years later and between 3 groups, either the basis that was not obtained having your own blood glucose value the patient watch is connected to the improvement of blood glucose management. Furthermore, the half of the patient who gives the blood glucose measurement equipment, had stopped use before the research period ending.

 Blood glucose self measurement with home, the patient is yourself and be able to adjust remedy, by facing in diabetes, are connected to conduct improvement it is assumed that you catch your own condition seriously, but according to Farmer, assuming, that there was that kind of effect, you say that they are small ones. From the latest result, the same person has expressed opinion that it should reform the current guideline regarding blood glucose measurement.

 Furthermore, self measurement with home in order to adjust the insulin prudently for the necessary 2 type diabetes patients of 1 type diabetes patients and insulin remedy, is indispensable, the usefulness is shown even from past research. Only 2 type diabetes patients who to the last do not use the insulin and, Farmer have expressed that it does not have the necessity of self measurement.

The danger which kidney artery extended technique brings

The danger which kidney artery extended technique brings


 The fragment of the abundant thrombus (the suspended matter) occurring with blood vessel formation technique and the [sutento] detention technique which expand the kidney artery which it blocks, it was shown having the possibility obstacle of doing to come to kidney function, American [ueikuhuoresuto] university Baptist Baptist medical center (North Carolina) by the research of Matthew Edwards doctors, was reported with the medical magazine “Journal for Vascular Surgery” June edition. As for research with the person who shows at microscope whether with this kind of disposal the suspended matter about which it occurs level, you say that this time it is unprecedented.

 With blood vessel formation technique and [sutento] detention technique of the kidney artery, inserting the balloon first, it expands the artery, it detains the tube in order to maintain the state next. This disposal is not observed when you compare to the similar operation which is executed in the heart blood vessel excessively, but you say that in the United States every year the presumption 40,000 ~ 80,000 person has received this remedy. This disposal main object, block to depend 高 hypertension ease do thing with, final goal kidney incompletion prevention be be.

 This time, the research team after the [sutento] detaining picking concerning the patient 28 example which receives blood vessel formation technique the blood inspection body. The result of inspection, you could see even 2,000 suspended matter particles in the inspection body, there was also a particle of size of the extent which makes the small blood vessel of the kidney block in. The number of particles which are found after that you can see relation in kidney function, extent and the kidney function where the suspended matter is many were defective.

 When from past research of the same group, there is decrease of kidney function after the kidney artery [sutento] detaining, the heart seizure after, it is found, that risk of stroke and the death becomes high, “it is something which is connected to the deterioration of long-term health state of the patient”, that Edward has expressed.

 In addition, capturing the suspended matter in the blood after the technique, making use of the protection instrument which it removes, what you can see the suspended matter was ascertained. As for the research group using, at one among the devices which presently is test stage, those due to the design of the American Medtronic [medotoronitsuku] corporation. Presently, the American food medical supply bureau (FDA) there is no device which receives approval, but sooner or later it is thought that it reaches the point where this kind of device is used on medical site.

 On the one hand as for Edwards, the fat plaque of type of a certain specification, pointing out the point which generates especially the abundant suspended matter in comparison with other ones. In the future, this most dangerous type as for Edwards you expect that it can specify before the technique. Concerning the carotid artery from the research which already uses MRI and the ultra wave, the plaque which is easy to cause the suspended matter has specified, the same group says that presently it has tackled the test which searches this point.

Decrease of olfactory sense in estimate factor of Alzheimer's disease

Decrease of olfactory sense in estimate factor of Alzheimer's disease

The possibility decrease of the olfactory sense being early sign of acknowledgment obstacle was shown, was published to the American medical magazine “Archives of General Psychiatry” July edition. The american rush Rush Alzheimer's disease center which leads research (Chicago) Robert S of nervous psychology professor. according to Wilson, what already you can see the decrease of the olfactory sense in the person who has minor acknowledgment obstacle is reported to the past, but as for designating the person who completely does not have acknowledgment obstacle when starting the research as the object you say that this research is unprecedented.

 In the latest research, targeting senior citizen 589 of average age approximately 80 years old, you make the smell of 12 types smell, carrying out the olfactory sense inspection which respectively makes the same smell choose from four choices. After that, inspection of nervous function and acknowledgment function year 1 time and 5 years it went. During research period 117 people early sign of the Alzheimer's disease emergence the minor acknowledgment obstacle which is doubted. As for the person where record of olfactory sense inspection is under average, emergence ratio of minor acknowledgment obstacle 50% high thing it was understood in comparison with the person who is above average. As for the result, the Alzheimer's disease starts from obstacle of the specific region of the brain, when it is something which agrees to the thought that spreading and keeping damaging the thought territory Wilson has expressed.

 American Alzheimer's disease association (AA) Gandy Doctor SAM of medical scientific Advisory Committee although this theory approximately is supported, you insist, that olfactory sense inspection becomes index of acknowledgment obstacle, points out that the appraisal with double blind method with the second and third group is needed.

 The developer of the olfactory sense inspection which is used in the latest research, Richard L of American Pennsylvania university medical center. according to Doty, you call this inspection that it has already been utilized at the clinical place. The parkinson's disease and the person who has the patient of the Alzheimer's disease in the blood related person targeting in the result and after carry out this inspection the disease in the person who emerges what you can see the decrease of the olfactory sense is shown, says that the nervous course medicine which utilizes this inspection in diagnosis of discrimination it is.

 It can execute this inspection in about 5 minutes, but now when according to Wilson, there is no effective cure which stops the advance of the Alzheimer's disease, you say that it is not the case that, everyone should receive this inspection directly. But, the medicine which designates the amyloid accumulation of the brain as the target being promising is shown and the remedy which if stops the advance of the disease becomes possible, you say that there is a meaning even in early detection. However, it is not olfactory sense inspection independently diagnosis even with in that case, we have assumed that it means to be used as one among various methods.

Popularity of the overseas medical tour which increases in the United States

Popularity of the overseas medical tour which increases in the United States


 In the United States, high level and seeking the medical care of price low attendant upon soaring of medical expense and increasing the non insurer population, you say that the person who goes out to “the medical tour” to the foreign country is increased rapidly. According to the statistics 2005, in the United States hit 15% or more of population approximately 4,500 ten thousand people who in insurance not yet joining. The person who in 2006 goes out to overseas travel with medical purpose estimating little, is estimated that it redoubles, in 2007 with 150,000 person or more.

 The medical tour company which is cooperated with the special travel agency has been born successively in the American all earth, also the insurance company of part has joined to this match. For example in California state, medical insurance company Health Net targeting the insured of Latin American type, exceeding the border, it executes the program which can receive medical care in Mexico. In addition, at another insurance company, year 400,000 the [bamurunrado] international hospital of the tie which is accepted (Bangkok) with to receive remedy it is possible the patient from the foreign country.

 Amount of the medical expense which can be saved with the medical care which exceeds the border is large. For example, when heart bypass technique is received inside the United States, 130,000 dollar (approximately 1,560 ten thousand Yen) the place where it requires, in India 10,000 dollar (approximately 1,200,000 Yen), with the tie 10,000 1,000 dollars (approximately 1,320,000 Yen) may be. But as for cost of crotch joint substitution technique, in the United States 40,000 3,000 dollars (approximately 5,160,000 Yen), in tie or Singapore 10,000 2,000 dollars (approximately 1,440,000 Yen). As for uterus extraction technique, in the United States 20,000 dollar (approximately 2,400,000 Yen), in India 3,000 dollars (approximately 360,000 Yen). Also the hospital of the foreign country which receives recognition the system JCAHO which you appraise & recognize the American medical treatment facility and the like (the American medical treatment facility appraisal joint committee) with international section Joint Commission International increases.

 Of course, it is not the case that completely it is not risk in medical tour. The person who “remedy is thought the leisure next” it is, but when you urge favorable recovery and in order to hold down the risk of the complication, leisure behavior such that you pass at the seashore you should refrain, the specialist points out. In addition, unless the hospital and the doctor are chosen prudently, besides the fact that there is a possibility remedy level being low, also the possibility medical tour becoming infection enlargement route of the disease is pointed out.

 The hospital is chosen through the agency even with, you verify the presence of recognition in advance, concerning the number and success ratio of executions of operation you say that it is important to inspect properly. The specialist is accustomed to catching, also that you discuss with the doctor well recommends. Medical tour to here at the presently it develops, kind of the fact that is denied to the [mu] [ge] to the doctor is when it is little.

The expectation which increases in the breast reconstruction which uses the fat of the patient himself

The expectation which increases in the breast reconstruction which uses the fat of the patient himself


 You say that the method of reconstructing the breast making use of the fat which was picked from the abdomen and the thigh of the patient himself, gets near to actualization. As for this it is called “Celution” new technology, the American Cytori Therapeutics corporation (San Diego) those which were developed. It cannot utilize with the United States yet, but in Europe the research which deals with the woman who receives breast part excision technique this year (2007) is started in, you say that it is the possibility that it reaches the point where it can utilize in 2009. (Editorial staff note: In Japan at the Kyushu hospital, clinical test of the breast reconstruction which uses beginning Celution for the world is done from 2006 May.)

 This news was published to the English industrial magazine “Chemistry & the Industry” July 9th number with the index, “lunchtime Yutaka chest”, but as for this when it is the expression which causes misunderstanding Eric Daniels doctor and Tom Baker doctor of the Cytori corporation have expressed. It requires 2~3 time for disposal at least, although there is also a possibility of being utilized in the future in the Yutaka chest, it says that at present time it is something which deals with the patient who receives breast part excision and tumor picking out removal.

 With this hand skill first, it extracts adipose tissue from the patient due to the disposal like fat absorption, this after 1 hours or more processing with the Celution system, the playback cell (regenerative cell) it fills to the breast of the patient. The various cells are included in adipose tissue, but as for carrying out important role in reconstruction when it is the trunk cell and the playback cell, Baker has explained.

 American [bibari] Hills (California state) with according to Brian Kinney doctor who serves the formation surgeon, with the plastic surgery fat fill is used generally from before approximately 15 years, although around the eye and the pleat of the nose lip groove, unevenness after the fat absorption technique is arranged, is utilized. Approximately, it reached the point where fat fill to the breast is examined from before the 6~8 year, but the doctor who is executed says that it is little. In addition to the problem that, the fat is easy re-to be absorbed, the fat which re-was absorbed on [manmoguramu] the breast cancer (the cancer) the way it is visible, the point where the identification is difficult feels concern. In addition, also the possibility the aftereffect being possible is pointed out.

 But, if problem of re-absorption is solved, when in the future also the Yutaka chest and the possibility of being utilized in breast reconstruction greatly there is this hand skill, Kinney has expressed. However attention was attracted several years ago, concerning the article, “lunchtime Yutaka chest”, to “weekend similar fairing”, we should trust, unless, you have commented.

With heart CT scan the cancer (the cancer) risk increase

 The report that was published to the American doctor periodical “JAMA” July 18th number cancer risk of the especially woman and the young person increases the CT crown artery contrast which decides the presence of heart obstacle (CTCA) with inspection. American Colombian University which leads research (New York) Andrew J. Doctor Einstein, has expressed that the doctor when choosing appropriate inspection method for the patient, it is the expectation where this knowledge is useful.

 The united states Scott & the White hospital (Texas state) as for Gregory Dehmer doctor, quite being useful by CT, although the picture which is superior it is obtained, as for the patient disclosing to abundant radiation it had already been informed, but as for this research you have expressed that it is something which verifies that. It is important for the doctor, the case where the blood vessel contrast due to CT is suited when it is to recognize the case which is not suited sufficiently the same person points out.

 The crown artery disease (CAD), the artery which supplies the blood to the heart hardens and in the disease which strangulates, in the United States both the man and woman has reached 1st rank of cause of the death. But as for the most standard diagnostics those due to crown artery contrast, because in this inspection it is necessary to insert the catheter into the blood vessel, heavily is serious times when the complication is caused there are, the inspection method whose invasive characteristic is low was required. It is CTCA where the one of them is approved in 2004. CTCA sensitivity and the degree of uniqueness can be high together inspect the presence of the disease quickly the urgent treatment room (ER) the chest which is conveyed painfully concerning the patient.

 But, the cancer risk due to this inspection was not so far quantized. In the latest research, the life cancer risk due to the radiation disclosure of 64 slices CTCA making use of computer simulation, was appraised. As a result, life cancer risk with 20 year old women had 3,261 1 and width with 1/143 and 80 year old men. But when ECTCM (the cure which makes the lighting quantity decrease with one section of heart period) with the method of saying is used, cancer risk respectively goes down to 5,017 1 with 1/219. Although always the choices which are optimum you cannot call CTCA for the young person and the woman for the patient of advanced age as for risk that much high thing became clear vis-a-vis the profit.

 As conclusion, is a chest painfully, the crown artery disease is really doubted is, kind of when, it is good making use of CTCA with the judgment of the doctor, but unless it is recommended, Einstein you express that CTCA is used easily with purpose of the mere medical examination.

The cancer (the cancer) the control protein (the protein) prevents also aging

The cancer (the cancer) the control protein (the protein) prevents also aging


 In p53 and the cell adjustment factor Arf which are known the cancer (the cancer) the control protein (the protein) as, having the function which can delay aging the Spanish national cancer research center (Madrid) was shown in research Manuel Serrano, was published to the English scientific magazine “Nature” July 19th number.

 For the cancer researcher, it is the substance to which the p53 protein adapts and is deep. p53 is made with the organism, there is the function which removes the cell where the risk which is converted malignantly is high, Arf assumes that that function is helped by informing about the cell which it should remove in p53. Serrano, in order to reveal p53 and Arf excessively, the gene the mouse which was operated while many years use for research, life of this mouse became aware in being longer than the other mouse.

 In the latest research, the cell which was picked from the p53/Arf excessive production mouse in detail examination. It could recognize the delay of the result and aging which inspected the aging marker, the cancer depression effect was considered and furthermore it became clear to be able to see the extension of life.

 As for Serrano, as for aging being controlled by p53 and Arf, when the cancer is controlled, opinion is expressed that completely it is the same reason. Aging defect of the cell accumulating, is thought that it occurs, but when as for p53 and Arf in a manner of speaking being something which bears “the quality control” of the cell, about the mouse whose p53 is many the cell is harshly managed, to become also aging it is loose difficult in the cancer, Serrano calls.

 The american stand age increase laboratory (NAI) according to Felipe Sierra, when life gets near to end in any Mammalia, emergence ratio of the cancer rises suddenly, but you say that you can explain the reason with p53. Nearly 80 years in case of the person who lives, it is necessary to prevent the cancer just that over the long period of time, p53 has helped that. While being young, p53/Arf has prevented the cancer, but when you grow older, when the effect becomes weak, the same person thinks. Everyone having close relationship to aging and the cancer as for felt, but as for the latest research you say that it is something which shows the basis.

 But, those like the Hurou immortal medicine do not have to be expected directly. The numerous chemical substance which makes p53 of in vivo increase it is developed by the major medicine manufacture company, but still at extremely early test stage, as for adjusting the action of p53 precisely unless it is easy, Serrano indication. Sierra with the same opinion, to the last fundamental mechanism just became clear, as for those where the operation is discussed with timewise prematureness, “young, the spring” has expressed that immediately there is no there.

With diabetes medicine heart failure risk in 2 times

With diabetes medicine heart failure risk in 2 times


 Diabetes remedy Avandia ([abandeia] and general name: rosiglitazone [roshiguritazon], in the Japanese country not yet approval) or [akutosu] ([pioguritazon]) as for the patient who uses each of them, the report that, was published to the medical magazine “Diabetes Care” August edition the emergence risk of heart failure is 2 times in comparison with the patient who is not used. The same family ([chiazorijin] system) with the medicine which belongs, the diabetes patient who exceeds 3,000,000 person in the United States has used Avandia and [akutosu]. In current label indication, in order to avoid the combined use with the use and the insulin with the grave heart failure patient, it is warned, but according to the latest knowledge, you say that risk increase could recognize to also the patient who does not correspond to this.

 The american food medical supply bureau which is announced to the preceding day of this report (FDA) in the research by the review team, when Avandia the risk which brings heart obstacle in comparison with [akutosu], is high substantially, the result was shown. According to the New York times paper, with the patient who has already used the insulin as for the side effect it is assumed to combined use with [akutosu] and the insulin vis-a-vis the risk due to especially Avandia being large, that it is not. This data is something which relates to the sale continuation of Avandia, whether or not the profit due to remedy exceeds risk when is important, one person of the team of FDA has expressed.

 In research “of Diabetes Care” publication, the American [ueikuhuoresuto] Wake Forest university (North Carolina) Sonal Singh doctors of the medical department, collecting the data patient 70,000 8,000 or more either Avandia or [akutosu] is used. As a result, besides the fact that it could recognize redoubling the heart failure risk, what you can see risk increase as high dosage low with whichever of dosage was ascertained. Average period to heart failure emergence from start of use of medicine 24 weeks. 25% of emergence examples under 60 not to be restricted years old and, to just the senior citizen, both the man and woman being seen it was recognized. As for the research group, as for cause of risk increase that we have presumed, whether it is not something due to moisture storage you have expressed that it is necessary to amend the current guideline.

 This year (2007) when the American Cleveland clinic (Ohio state) Steven E. Nissen, heart seizure risk 43% increases with the use of Avandia, we announce knowledge to May, argument is continued even now. According to the New York times, as for public information charge Mary Anne Rhyne of the production original [gurakuso] [sumisukurain] corporation of Avandia, as for opinion of the same company which we assume that the same medicine is safe, vis-a-vis the review of FDA, you have expressed that it does not change. With the data of the same company increase of the heart blood vessel death with Avandia is not recognized, you say that either difference of heart seizure emergence ratio is not recognized with the other medicine. Andy Zambanini doctor of the same company clinical development patsy says that presently FDA and negotiation are continued concerning the new alarm display regarding heart failure.

 But as for Nissen, as for the patient who examines the use of Avandia the doctor it should consult well, just this news should stop the medicine which presently has been used for the reason, unless, opinion. The american diabetes association (ADA) Larry Deeb, if you use each medicine just, insists that it is safe. But as for the heart failure risk by both medicines in 50 1 people, if it is possible to ascertain the 1 people, to express that it is possible to remedy 49 people who remain safely because you can see the risk increase of heart failure and the heart seizure, saying, if it is not and uses the necessity to discontinue marketing both medicines appropriately it has expressed opinion that it is the useful medicine.

(Compilation gathering =FDA as for Advisory Committee July 31st at the commission which is held, as for possibility of the heart diseased risk increase of Avandia although it recognized, sale continuation of the same medicine was approved with majority of 22 to 1.)

The cancer (the cancer) the new inspection method which early makes diagnosis possible

The cancer (the cancer) the new inspection method which early makes diagnosis possible


 The cancer of early stage (the cancer) the possibility where it can inspect safely and accurately was shown in small-scale extra research, was reported with the medical magazine “Clinical Cancer Research” August 1st number. The cell of the duodenum which was picked due to endoscope biopsy, when is inspected making use of light scattering, with when there are no with times when there is cancer, you say that the scattering effect which is different is shown.

 The american [nosuuesutan] university which leads research (Illinois state [ebansuton]) as for Vadim Backman, the patient who has the family history of the cancer due to this method, risk you have expressed that there is also a possibility of reaching the point where dying every year it can receive inspection. cancer action network (PanCAN) also Julie Fleshman, while we assuming, that furthermore detailed research is necessary, this inspection has shown expectation in the possibility of becoming the important tool for the patient.

 The large star of the opera boundary, [ruchiano] [pavuarotsutei] presently as for the cancer which is known by also the fact that the fighting illness it has done, when condition appears, having already spread to the other internal organs is many, as for 5 year survival ratio under 5%, in 3 people as for 1 people from diagnosis you die it is the fearful disease within 1 years. With scan technology in addition to discovering the 膵 cancer of early stage, biopsy and the stab (the plug and so on to do) in the inspection whose invasive characteristic is high the risk which the complication does to come heavily seriously is also 20% or more, it assumes that they are the internal organs whose treatment quite is difficult.

 The research team had already pinpointed the fact that early of the colon which it adjoins from the inspection body which was picked in the rectum biopsy making use of the technology due to optical spread, the cancer can be inspected. From this, the pancreas nearly it is located immediately, pays attention to the easy duodenum of biopsy picking. Organization of the duodenum was extracted from 51 subjects, due to endoscope biopsy. Portion of the subject is the patient who already has the cancer of various illness periods. In the cell where it picked, the result of carrying out the optical spread inspection of 2 types, early and 100% it was possible to inspect the cancer of the latter term. There was a false positivity of several examples, but you do not know whether this being the mere mistake, whether in the future that subject the cancer it is something which shows the fact that the risk which emerges is high.

 As for Backman, as for this inspection it has emphasized that it is something which deals with the person who to the last has the family history of the cancer. [manmoguramu] of the woman (breast X-ray inspection) and PSA of the man (the prostate unique antigen) in inspection the way when still it is distant, Fleshman calls the actualization of the cancer inspection which can be executed widely generally. The team Backman has tackled the large-scale test which already deals with 200 people or more concerning this light scattering inspection. Besides the fact that the cancer and when discriminating the other benign diseases, usefulness are examined, you say that the person who has the family history it is the schedule which also comparison of the person who is not does. Fleshman, although big expectation is moved aside to possibility of this inspection, furthermore points out the point where huge cost is necessary to cancer research.

The cause protein of the Alzheimer's disease (the protein) participates in also glaucoma

The cause protein of the Alzheimer's disease (the protein) participates in also glaucoma


 Old person unevenness (the plaque) the amyloid which is formed - ## (beta) the protein (the protein), the possibility of becoming cause of retina cell death in the glaucoma it was shown in the brain of the Alzheimer's disease patient, “Proceedings of the National Academy of Science (PNAS)” of the American scientific academy issue August 7th was published to online edition (printing edition August 10-16th in the number publication).

 In the latest research, the English London university (UCL) M. as for Francesta Cordeiro doctors, vis-a-vis the rut/rat which in order to emerge, operated glaucoma the amyloid - when the medicine which obstructs the formation route ## is used, the damage of the eye lightened, life of the retina cell extended. When obstruction of formation route was tried with method of several types, when the effect is highest in 1 types among those, jointly uses the method of all type, you say that furthermore you could see the big effect.

 As for this knowledge, there is also a possibility of becoming the key which solves the doubt which has surfaced recently between the ophthalmologists concerning glaucoma remedy. To several years ago, glaucoma is stated when it is something where retina cell death happens with the abnormal rise of eye pressure, the remedy which presently lowers eye pressure mainly is done, but to tell the truth as for eye pressure normally close thing has known above the half of the glaucoma patient. We have assumed that the American ophthalmology academic society (AAO) presently, eye pressure rise it deletes the description which we assume, that it is cause of glaucoma, simply main dangerous factor (the risk factor) is.

 As for Corderio, the amyloid - you observe to ## by the fact that you could see the retina cell death which is similar to glaucoma in the Alzheimer's disease patient. Besides the fact that the amyloid - it could recognize the accumulation ## in the retina cell which becomes extinct, when the amyloid - it adds ## in the retina cell which was cultured cell death being induced it was recognized. When also the possibility where it can remedy the Alzheimer's disease the eye from this research, as the entrance of the body using it is Corderio has expressed.

 The american duke university (North Carolina) Stuart J. McKinnon doctor, method of thinking where there is a root of this research although it makes proper, there is no animal model where eye pressure glaucoma is superior low, in the latest research, pointing out the point which uses the rut/rat model which emerges glaucoma to a high eye pressure. Appraisal has expressed that it should make prudent. In addition, also cause of cell death being unclear, you do not know whether being the difference of the gene, whether it is difference of the sensitivity for eye pressure. But, it is certain, for the road to the new cure where in any case the amyloid - it designates ## as the target to be opened sooner or later when also the possibility of the vaccine actualization which prevents plaque formation it is as for the specialists you express.

Stroke RIsks of Woman

The woman who has one headache stroke risk is high


 The woman who has the one headache which accompanies visual condition as omen, when especially smoking and the contraceptive are jointly used, was shown by the research whose it is new, for risk of stroke to be high, August 9th was published to American medical magazine “Stroke” online edition (printing edition September edition publication).

 According to Steven Kittner doctor of the American Maryland university medical department which leads research, the group of the woman of the 15~44 year which has one headache stroke as for the risk which emerges 20 people quite is small concerning 100,000. But, when that woman is the smoker and when there is a hypertension or diabetes, stroke risk becomes high.

 As for the latest research, stroke those which are compared with the woman 614 person of the same age which of the 15~49 years which have the fact that it emerges collects the data 386 of women, does not have the case history of stroke. As a result, as for the woman who has the one headache which accompanies visual condition stroke risk was 1.5 times in comparison with the woman who does not have one headache. Furthermore, among the women who have the one headache which accompanies visual condition, as for the woman who use the contraceptive and smokes, stroke risk was 7 times in comparison with the woman who has neither. You say even with when one headache starts recently that in the same way as the case where there is a frequent one headache and a long term one headache, there is a possibility of bringing the increase of stroke risk.

 As for the one headache having visual condition the dangerous factor whose stroke is weak (the risk factor) as it is necessary to consider, itself concerning it is not possible either how to do, but it should take some kind of preventive step when it influences, Kittner expresses, the woman who has same condition stops smoking, that it is necessary to discuss with the doctor sufficiently concerning the use of the contraceptive has advised.

 The american [burigamu] and [uimenzu] hospital (BWH, Boston) as for Tobias Kurth doctor, as for one headache and the research which shows the relation of stroke risk large number it is executed even so far, but the latest research being something which shows the fact that that risk increases with other factor, recommends the prohibition of smoking of the woman who has one headache. However if it remedies one headache, whether or not stroke risk decreases, there is no data and concerning, it is with unclear.

s for the Asian human man the prostate cancer (the cancer) convalescence is satisfactory

According to Anthony Robbins doctor of the California cancer register mechanism, the Asian type man says that survival ratio is high in comparison with the white. But, the man of south Asian type survival ratio is lower than the black and the white rather. Furthermore, when the Asian human man age when diagnosing is high relatively, dangerous factor (the risk factor) sees from the surface although on the other hand it is disadvantageous expectation, as for survival ratio high thing was found.

 In the latest research, the white 100,000 8,076 people and the Asian person who were diagnosed the prostate cancer (China, the Philippines, Japan, Korea, south Asia and Vietnam) the data 8,840 total 110,000 6,916 was collected, convalescence factor and survival ratio were compared. As a result, the tendency where, the Asian person reaches, the disease advancing, receives non heal remedy and reaches was high, in the aspect of dangerous factor more defective than the white. But the Asian person (excludes the south Asian person) as for survival ratio same as the white above that, as for the Japanese-American the mortality rate due to the prostate cancer 34% was lower than the white. On the one hand, south Asian system (India, Pakistan, Bangladesh, Sri Lanka, Nepal and Bhutan) as for mortality rate you say that 40% it was higher than the white.

 You can think dietary life, motion and heredity etc as the factor which brings the result, as for the doctor after considering this kind of difference, when remedy plan and it is necessary to notiify survival ratio, Robbin has expressed. The american cancer association (ACS) Durado Brook doctor, in this research, the former way when the south Asian human group is handled the other Asian people and together, points out that is not unable leading erroneous conclusion was shown. According to ASC, in 2007 approximately 210,000 8,890 people are diagnosed the prostate cancer anew in the United States, it is presumed that approximately 20,000 7,050 people die. However, as for mortality rate there is a decrease tendency depending upon early detection.

 In another research which is published to the same number, as for the black woman survival ratio of the breast cancer low thing was ascertained regardless of the stage of the cancer. Even, so far, as for the black woman the tumor was informed to be large invasive characteristic is high is easy to fall sick in the breast cancer whose being the tendency which, but in the latest research by the breast cancer of the black woman the mortality rate it became clear as many as 56% to be higher than the white. You have expressed that it is suggested that the primary factor which is not the clinical factor such as quality of ratio and the remedy which as for the research group, as for differential of this survival ratio are large unexpectedly, receive remedy has exerted influence.

The fire-resistant chemical substance is related to the thyroid disease of the cat, has an influence on also the person?

The fire-resistant chemical substance is related to the thyroid disease of the cat, has an influence on also the person?


 Is seen mainly in the American house cat the thyroid function of the cause obscurity which 亢 the Shin symptom, the carpet, the furniture and the mattress, the electric product, furthermore is included in also the pet hood the fire-resistant chemical substance which (fire-retardant chemicals) is the poly- bromination diphenyl ether which (PBDE) due to the possibility was reported. This substance as for the basis of harmfulness is not shown in the person, but you say that it cannot deny either the possibility.

 The american protection of the environment agency which executes research (EPA) Linda S. according to Birnbaum, the being disclosed level to PBDE the cat is much higher than the person. Thyroid function 亢, weight decrease and appetite 亢 Shin, there is a dehairing and a excitability etc with the condition which the cat of the Shin symptom shows. In the most lethal disease, the cat which is raised in the especially interior risk is high in the cat of old-age. Because the body [zu] [ku] [ro] is carefully in the cat and there is a habit which is done, it is thought that it is easy to take in the house dust which includes PBDE to internal.

 To the healthy influence of PBDE problem apparent as for reaching the point where it is done nineties latter half. The liver virulence and nervous virulence of PBDE are shown in animal research, it is found that it is relationship with the house dust and breast milk PBDE density. Although many of PBDE it has decreased with the independent movement of the manufacturer and the regulation of government, because it is the substance which is difficult to be disassembled it disappears from environment until, you say that long time is required. The furniture manufacturer presently has used the alternative substance.

 In latest research which is published to American environmental scientific magazine “Environmental Science & Technology” online edition on August 15th, 23 cats (inside 11 thyroid function 亢 the Shin symptom) picking the blood inspection body. As for the cat which has the disease, PBDE value was 3 times in comparison with the young cat and the cat which does not have the disease. PBDE is recognized by also the can entering cat hood, is many in those of the especially fish flavor. The result of analysis, the feed as for the can entering hood central cat, was 12 times that when PBDE value is the dry hood. As for PBDE disclosure of the cat, you say that it can reach also 100 times that of the American adult.

 Thyroid function of the cat 亢 reaching the point where you can see the Shin symptom started being utilized before approximately 30 years, same time PBDE in the interior supplies. As for the United States being the world, the utilization of PBDE is most, PBDE value of the person and is highest in the world, it is thought that the same diseased risk of the cat are high. Presently the same disease is recognized even at Canada, Australia, Japan and European every place. Also the affection of the person increases, for example bush former American president and bar rose lady, furthermore also the dog which the husband and wife raises has contracted a disease.

News From japan

ancer patient, before the remedying ovarian retention - - after the recovering, opportunity of pregnancy

 Sterile remedy special Kato [redeisukurinitsuku] (Tokyo & Shinjuku), in order to prevent the fact that in the side effect of cancer remedy it becomes the sterility, the January this year, portion of ovarian organization was picked from the cancer patient of 20 generations, freezing retention was executed. According to mulberry tree mountain correct forming Chief of Research and Development of the same clinic you call “new attempt in the country”. It announces at the Japanese fertilization imbedding academic society which from 30 days starts in Sendai city.

 In order with cancer remedy to use radiation and the carcinostatic substance, there are times when hypofunction of the ovary happens in the side effect, becomes the sterility. Beforehand, if picking the portion of the ovary it retains and resets after the remedying the opportunity of pregnancy can be offered to also the cancer patient who so far abandons the child.

News from japan

The [keita] 75 year old be able to look upward from here from administrative director, premium of the medical system, as for the upper limit in year 500,000 Yen
2007 August 04th

 In the medical system which deals with the latter-term senior citizen of 75 years old or more where you start from 08
Being, as for the public welfare Ministry of Labor the upper limit of premium per 1 deciding the thing which is made annual 500,000 Yen
It is. For the household whose income is high from now one side where the possibility premium burden increasing is high,
In & low it installs also the measure which lightens the burden of income earner layer.

 Presently, the national health insurance (National Health Insurance) where large portion of the senior citizen joins with joining of the family unit, 1
The upper limit of burden around household has reached annual 560,000 Yen. As for latter-term senior citizen medical system
To become joining of the human unit, so far, having become the suffering supporter of the husband and the child of the office worker, preservation
Also the person who does not bear severe charge, bears premium anew.

 The upper limit of burden with the new system, to income the uniformity which insured everyone pays the income percentage which extremely responds
It adjusts, per 1 people it reaches 500,000 Yen by the fact that, premium burden of high income household past
The [ri] there is a possibility of increasing.

 On the one hand, it is low with income household, burden of equal percentage according to the annuity earnings and the like of the married couple 7 tenths,
5 tenths, 2 it is lightened extremely. Vis-a-vis the person who means to bear premium anew 2 years
Besides the fact that income percentage is exempted between, as a sudden change relief measure, equal percentage becomes half price.

 With the estimate where the thick labor ministry does at 05 year point in time, as for the average premium per 1 month amount 620
0 Yen. But, actual premium level to differ depending upon the metropolis and districts, per senior citizen 1
About the self-governing community whose medical expense is high also premium becomes high. Present National Health Insurance premium every of municipalities
Differential is large, whether the thick labor ministry “with the new system becomes burden increase, or becomes the burden decrease, unconditionally
You cannot say”, that it has done.

 As for the latter-term senior citizen medical system, 75 years old or more classified by because the person where medical treatment is prolonged is many, the system of building
E.g., is necessary, that it is possible with policy of the thick labor ministry which is done. Because public finance is made to stabilize, management of insurance
To make the metropolis and districts unit, as for the revenue source with premium of main person of the senior citizen 1 tenths, support from the active generations
With the gold 4 tenths, 5 it is planned extremely with public funds.