Wednesday, December 12, 2007

cells from human skin cells fabricated universal success

Kyoto University and the American University of Wisconsin two research groups almost simultaneously, skin cells from human embryonic stem cells (embryonic stem cell: embryonic stem cells) very closely versatile cells that produce success.

ES cells of the body with the ability to become any cell pluripotent cells in the treatment of various diseases potential use is expected to gather.However, stem cells taken to the subsequent growth that can destroy the embryo must be the ethical aspects of the discussion by calling. The second study showed how embryos are not used for such a discussion to avoid it.

University of Wisconsin researchers who led James Thomson, "said stem cells essentially the same thing from a mature cell is shown how to produce it in the ethical discussion has been a change brought about," he said .Meanwhile, Japan's Kyoto University who led the study of the mountains of Wataru Shin professor, "This cell is the understanding of the disease mechanism and the effective and safe drug development, such as cell therapy could help," he said.However, treatment can be applied until the road is distant and the Texas A & M University Health Science Center, said Robert Tsai said.the mountains, they will study medical journal "Cell" on November 30 issue of the University of Wisconsin study of "Science" online edition on Nov. 20 appeared.

  Both teams using fundamental principle is almost the same in the mountain's team, the retrovirus (cancerous cells associated virus) using skin cells to the four genes embedded. University of Wisconsin team in the mountains, they are using gene is two different things. Fabricated "iPS cells (induced pluripotent stem cell: induction pluripotent stem cells)" is the appearance of cell culture and nature in terms of the ES cells ME very similar to that of the 30,000 pieces of genetic strength of the results examined the approximately 1,000 gene expression is different in that it is OK.

IPS this human cells, ES cells to replace and determine whether the need to further study after another.
Thomso. IPS cells by the emergence of stem cell research is not the end, the future of stem cell research is used as it is supposed to be scarce and Thomson said.

Yamanaka said, fabricated using a retrovirus because iPS cells with carcinogenic possibility that the safety check can also challenges for the future. Also, iPS cells from the sperm and egg cells produced by the cell in iPS ethical problems arise.To avoid misuse, iPS human cells manufacture and use of the appropriate regulations to implement it as vital to the mountains, he said.

obese men have lower PSA values

Obese men are prostate cancer (cancer) index and PSA (prostate specific antigen) blood concentration is usually lower than the test results to adjust, but you must have known. The cause of the obese men, a lot of blood for PSA is diluted by the potential indicated by the American Medical bulletin "JAMA" November 21 issue reported.

Prostate cancer Fund (PCF) said that in the United States men's one out of six people in the prevalence of prostate cancer, the most in at least 65 years old. Many of the older men regularly received PSA blood tests, but a recent study from the excess weight and obesity in men with normal PSA values weight in males than 20 to 25 percent lower that were . Therefore, a large body of men, normally deemed to 1 to 2 years or more left while the cancer is growing and could have. Extremely underweight due to the impact of the presence or absence of PSA value of the deal were not disclosed.

The Duke University (NC) Associate Professor of urologic pathology Dr. Stephen Freedland said by this research is a large body of men's PSA value is low, the amount of blood due to the antigen was diluted by the to verify that hypothesis. 1988.From 1988 to 2006 between the removal of the prostate by prostate cancer examined patient 14,000 people about the result, the weight of so many men blood volume than is found. Diluted by PSA decrease in the level of having a theory and is backed by research group said.Freedland said the same thing to other blood cancer marker goes, "to develop a blood test for the product, it needs to take place," he said.

Meanwhile, the United States Medical University (New York) professor Nelson Stone, said the findings showed a skeptical view.This research has advanced prostate cancer patients, and only as a point of this and other factors will result in distortion might have said. However, a large body of people PSA value slimness and the same, but the value of PSA evaluation need to be careful that he also admitted.

CT scan extensive use of cancer risk is increased

The 1980s and later, CT scans in the United States is rapidly increasing the number of enforcement, which in conjunction with high-dose radiation exposure due to cancer (cancer) risk is increased that the American medical journal "The New England Journal of Medicine "November 29 issue reported. David J. Brenne Eric J. Hall. This report is the U.S. Columbia University (New York) David J. Brenner said Eric J. Hall, and they made that.

Currently, the United States is years 62 million more than the CT scan (X-ray using body cutaway to shoot imaging method) is in effect. CT scan is usually performed by X-ray of 50 to 250 times the amount of radiation exposure to, and the individual unit is a small risk, but a large group unit in the future issues will come up.

"Radiation - induced solid cancer incidence require long periods of time before (except leukemia within 10 years to develop that), after several decades are now being conducted in the CT scan attributed to cancer, cancer the overall 1.5 to 2 percent, "Brenner said. Also, the annual four million to 500 million CT scan in children is in effect, but the children are adults compared to more sensitive to radiation, abdominal CT scan 1,000 to 1 in the proportion of cancer risk both have been pointed out.

  Brenner said that the enforcement by CT scan one-third of the annual 20 million cases of diagnostic ultrasound, and other methods can also substitute the medical necessity of that. In recent years, the lung cancer diagnosis, virtual colonoscopy (virtual), whole-body CT scan, and also is used as it is becoming the most of the benefits outweigh the risks (benefit) that have been shown to be It does not, Hall said. However, CT is an excellent diagnostic method that is true, and appropriate use of blindly not be avoided They are also pointed out.

Brenner and Mr. Hall said the CT scan as a means to reduce the risk of the following three suggestions on that. The radiation dose to the individual patient to adjust, ultrasound and MRI (magnetic resonance imaging), and radiation risk-free alternative if you have to avoid the use of CT scans, CT scans reduce the number of enforcement - that . This allows the adult years, 20 million people, the children of 100 million people to avoid unnecessary radiation exposure can be.

Another expert, unnecessary CT scan that people are recognized.However, fears about radiation from the CT require a patient to get out of the CT response to the problem have said. The latest equipment in the radiation dose adjustments, and it is possible to use the dose can be reduced. Inadequate enforcement to ease the guidelines already in existence.