cells from human skin cells fabricated universal success

Kyoto University and the American University of Wisconsin two research groups almost simultaneously, skin cells from human embryonic stem cells (embryonic stem cell: embryonic stem cells) very closely versatile cells that produce success.

ES cells of the body with the ability to become any cell pluripotent cells in the treatment of various diseases potential use is expected to gather.However, stem cells taken to the subsequent growth that can destroy the embryo must be the ethical aspects of the discussion by calling. The second study showed how embryos are not used for such a discussion to avoid it.

University of Wisconsin researchers who led James Thomson, "said stem cells essentially the same thing from a mature cell is shown how to produce it in the ethical discussion has been a change brought about," he said .Meanwhile, Japan's Kyoto University who led the study of the mountains of Wataru Shin professor, "This cell is the understanding of the disease mechanism and the effective and safe drug development, such as cell therapy could help," he said.However, treatment can be applied until the road is distant and the Texas A & M University Health Science Center, said Robert Tsai said.the mountains, they will study medical journal "Cell" on November 30 issue of the University of Wisconsin study of "Science" online edition on Nov. 20 appeared.

　 Both teams using fundamental principle is almost the same in the mountain's team, the retrovirus (cancerous cells associated virus) using skin cells to the four genes embedded. University of Wisconsin team in the mountains, they are using gene is two different things. Fabricated "iPS cells (induced pluripotent stem cell: induction pluripotent stem cells)" is the appearance of cell culture and nature in terms of the ES cells ME very similar to that of the 30,000 pieces of genetic strength of the results examined the approximately 1,000 gene expression is different in that it is OK.

IPS this human cells, ES cells to replace and determine whether the need to further study after another.
Thomso. IPS cells by the emergence of stem cell research is not the end, the future of stem cell research is used as it is supposed to be scarce and Thomson said.

Yamanaka said, fabricated using a retrovirus because iPS cells with carcinogenic possibility that the safety check can also challenges for the future. Also, iPS cells from the sperm and egg cells produced by the cell in iPS ethical problems arise.To avoid misuse, iPS human cells manufacture and use of the appropriate regulations to implement it as vital to the mountains, he said.

obese men have lower PSA values

Obese men are prostate cancer (cancer) index and PSA (prostate specific antigen) blood concentration is usually lower than the test results to adjust, but you must have known. The cause of the obese men, a lot of blood for PSA is diluted by the potential indicated by the American Medical bulletin "JAMA" November 21 issue reported.

Prostate cancer Fund (PCF) said that in the United States men's one out of six people in the prevalence of prostate cancer, the most in at least 65 years old. Many of the older men regularly received PSA blood tests, but a recent study from the excess weight and obesity in men with normal PSA values weight in males than 20 to 25 percent lower that were . Therefore, a large body of men, normally deemed to 1 to 2 years or more left while the cancer is growing and could have. Extremely underweight due to the impact of the presence or absence of PSA value of the deal were not disclosed.

The Duke University (NC) Associate Professor of urologic pathology Dr. Stephen Freedland said by this research is a large body of men's PSA value is low, the amount of blood due to the antigen was diluted by the to verify that hypothesis. 1988.From 1988 to 2006 between the removal of the prostate by prostate cancer examined patient 14,000 people about the result, the weight of so many men blood volume than is found. Diluted by PSA decrease in the level of having a theory and is backed by research group said.Freedland said the same thing to other blood cancer marker goes, "to develop a blood test for the product, it needs to take place," he said.

Meanwhile, the United States Medical University (New York) professor Nelson Stone, said the findings showed a skeptical view.This research has advanced prostate cancer patients, and only as a point of this and other factors will result in distortion might have said. However, a large body of people PSA value slimness and the same, but the value of PSA evaluation need to be careful that he also admitted.

CT scan extensive use of cancer risk is increased

The 1980s and later, CT scans in the United States is rapidly increasing the number of enforcement, which in conjunction with high-dose radiation exposure due to cancer (cancer) risk is increased that the American medical journal "The New England Journal of Medicine "November 29 issue reported. David J. Brenne Eric J. Hall. This report is the U.S. Columbia University (New York) David J. Brenner said Eric J. Hall, and they made that.

Currently, the United States is years 62 million more than the CT scan (X-ray using body cutaway to shoot imaging method) is in effect. CT scan is usually performed by X-ray of 50 to 250 times the amount of radiation exposure to, and the individual unit is a small risk, but a large group unit in the future issues will come up.

"Radiation - induced solid cancer incidence require long periods of time before (except leukemia within 10 years to develop that), after several decades are now being conducted in the CT scan attributed to cancer, cancer the overall 1.5 to 2 percent, "Brenner said. Also, the annual four million to 500 million CT scan in children is in effect, but the children are adults compared to more sensitive to radiation, abdominal CT scan 1,000 to 1 in the proportion of cancer risk both have been pointed out.

　 Brenner said that the enforcement by CT scan one-third of the annual 20 million cases of diagnostic ultrasound, and other methods can also substitute the medical necessity of that. In recent years, the lung cancer diagnosis, virtual colonoscopy (virtual), whole-body CT scan, and also is used as it is becoming the most of the benefits outweigh the risks (benefit) that have been shown to be It does not, Hall said. However, CT is an excellent diagnostic method that is true, and appropriate use of blindly not be avoided They are also pointed out.

Brenner and Mr. Hall said the CT scan as a means to reduce the risk of the following three suggestions on that. The radiation dose to the individual patient to adjust, ultrasound and MRI (magnetic resonance imaging), and radiation risk-free alternative if you have to avoid the use of CT scans, CT scans reduce the number of enforcement - that . This allows the adult years, 20 million people, the children of 100 million people to avoid unnecessary radiation exposure can be.

Another expert, unnecessary CT scan that people are recognized.However, fears about radiation from the CT require a patient to get out of the CT response to the problem have said. The latest equipment in the radiation dose adjustments, and it is possible to use the dose can be reduced. Inadequate enforcement to ease the guidelines already in existence.

　

With magnesium risk decrease of metabolic syndrome

　The abundant food of magnesium being useful to the disease rate decrease of the metabolic syndrome which is connected to diabetes and the crown artery disease, it was ascertained by up-to-date research. According to the report which is published to the American medical magazine “Circulation” March 28th number, in the research which is started in 1985 the American approximately 4,600 people as an object, the person where the magnesium intake quantity is many says that after that metabolic syndrome emergence risk of 15 years 31% low thing became clear.

　The hypertension, the high blood glucose, other than the high fat blood symptom and the “virtue ball” decrease etc of the HDL cholesterol which is it is included in the condition of metabolic syndrome. When three or more among these can be recognized, the heart blood vessel disease and risk of diabetes increase. As for the research which shows the relationship of magnesium between metabolic syndrome it is not unprecedented, but the American [nosuuesutan] university (Illinois state) according to Ka He Doctor medical department assistant professor, you say that it was found that in the latest research anew “by the fact that magnesium is taken in mainly, risk of individual condition of metabolic syndrome decreases”.

　The halibut and the roasting almond, the cashew nuts, the spinach and all the grain serials, there is an avocado, a banana and a raisin etc in the food where magnesium is included. Among approximately 16% of the subjects has utilized the nutrition auxiliary food of magnesium (the supplement), also effectiveness of the supplement was shown.

　As for the feature of the latest research, the point which deals with the young person, 20 year old generations at start point in time mainly. But as for the young person in extending life indifference, from the result, also the young person should have interest in healthy dietary life, when it is found that, He has expressed.

　The american medical laboratory (IOM), 19-30 with the man of year old 1 days 400mg, the magnesium intake of 310mg is recommended with the woman. But, as for the role which magnesium carries out healthy for the heart you say that it is no more than an extremely part. As said generally, prohibition of smoking and motion, the vegetable and the fruit to be many also it is indispensable to refrain from the food where the taking in and the fat are many.

Lack of sleep is related with weight increase

The night securely by the fact that you sleep, not only being able to obtain sufficient rest, it can hold down the weight increase which accompanies age increase the research result that, it seems, the American chest academic society which is held in San Diego (ATS) was reported with the international conference. This the American case western reserve university (Ohio state) clear causal relation in the research by Sanjay Patel Doctors medical department assistant professor, although it is not shown, calls that you can see significant connection with lack of sleep and weight increase.

　This time, becoming the investigation object 16 years women 60,000 8,000 portion of the woman who participated in Nurses Health Study which or more is pursued. The subject reported 2 years concerning the weight and life habit of each one. The period end time, sleep time as for the woman of 5 hours, in comparison with the woman of 7 hours, 33 pounds or more (above approximately 15 kilometers) the ratio where substantial weight increase is recognized 32% was high, the ratio which had become obesity 15% was high. In addition, sleep time as for the woman of 6 hours, substantial weight increase 12% was more than the woman of 7 hour sleep, as for obesity 6% was many.

　“But as for the lack of sleep person as for the consciousness for generally healthily being low certain, as for the basis that it is not seen it has become cause of this weight difference poverty of dietary life and concerning, each factor such as motion insufficiency,” that Patel has expressed. Actually, as for the woman who everyday sleeps of 7 hours or more only 5 hours the meal quantity was more than the woman who is not taken, almost could see difference between both groups concerning the habit of motion.

　As a result you say that you can think several explanations, concerning. Besides the fact that you can think that caloric metabolism efficiency of the body decreases with lack of sleep, really there is also a possibility of having difference in method of exercising between both groups and tendency of the meal. Furthermore, the time when it applies to sleep it is little, change of the big kind of life where, but for example has the child, is thought is reflected also. When the extent sleep time where the number of children is many decreases, because it is chased in careless thing, is easy to become dietary life of convenience priority such as fast food Patel points out. In another research, it is suggested that sleep obstacle such as snore and nighttime awakening which are strong has had an influence on weight.

Diabetes and smoking dangerous factor of legs artery disease

If the peripheral artery disease that (the PROPELLANT-ACTUATED DEVICE), the presumption 8,000,000 ~ 12,000,000 person it is in the United States, in the disease which the peripheral artery blocks, the same thing happens with the heart blood vessel, it becomes cause of the heart seizure and the like. In the PROPELLANT-ACTUATED DEVICE, blockade the leg (the legs) it occurs in the large blood vessel when and, there are times when it occurs in the small blood vessel, it was reported, but that there is the decisive difference in these 2 types, with the medical magazine “Circulation” May 30th number the dangerous factor which differs respectively (the risk factor) it is.

　Condition differs respectively, when it occurs in the large blood vessel, the crotch joint and the thigh, wipes the PROPELLANT-ACTUATED DEVICE of 2 types, and others there is many a thing where the antalgic spasm which in the joint is settled in several minutes happens. In case of the small blood vessel, besides the fact that there is a cold impression, recovery of wounding becomes slow, heavily seriously with case there are also times when cutting is required.

　The american University of California San Diego school (UCSD) medical department professor Michael H. Victor Aboyans doctors of Criqui doctor and France and the Dupuytren university hospital, when starting the research and after that 4.6 years, the arm, measured the blood pressure of the finger of the ankle and the foot respectively the man and woman 403 person of the large blood vessel PROPELLANT-ACTUATED DEVICE concerning small blood vessel PROPELLANT-ACTUATED DEVICE patient 290, compared. As for index of the PROPELLANT-ACTUATED DEVICE, the blood pressure of the ankle 90% or less of the blood pressure of the arm, the blood pressure of the finger of the foot is 70% or less of the arm. This decrease ratio and diabetes, the hypertension, smoking and cholesterol value etc various dangerous factors of the PROPELLANT-ACTUATED DEVICE which is known so far were together examined.

　As a result, as for significant dangerous factor only diabetes it was found concerning the small blood vessel PROPELLANT-ACTUATED DEVICE, that is. As for the most significant dangerous factor of the large blood vessel PROPELLANT-ACTUATED DEVICE with smoking, as for the smoker the ratio which deteriorates substantially in comparison with the non smoker 3.2 times was high. You say that also high cholesterol becomes important index. It did not become with clear index mass drinking (week 21 container of or more) and concerning the hypertension.

　According to Aboyans, “as for being most unexpected, you say that diabetes being unrelated in advance of the large blood vessel PROPELLANT-ACTUATED DEVICE” is. Criqui, points out that it is important to measure the both blood pressure of the finger of the ankle and the foot concerning the patient who has especially diabetes. In addition, as for the latest result, the anti- solidification medicine and when the remedy by the cholesterol decrease medicine star chin it is something which supports the current PROPELLANT-ACTUATED DEVICE remedy guideline which recommends, in addition also the anti- blood platelet medicine like aspirin it is effective Criqui has expressed.

Whether or not as for high dosage star chin danger with argument boiling

When the star chin type medicine which is the cholesterol decrease medicine is used with high dosage the criticism to which the dissertation that is announced, is strong at part risk is high, is called. In the United States, for heart diseased risk reduction there is a tendency which promotes positive cholesterol decrease, but the English doctor periodical “British Medical Journal (BMJ)” in the report which is published to the June 3rd number, danger of the high dosage star chin was pointed out. Those which as for the American specialists, as for this insistence showed the effect and safety of the high dosage star chin and ignored knowledge many you have refuted.

　The american cholesterol educational program (NCEP) last year (2005) with the opinion which is shown, as for the patient whose heart diseased risk is very high have assumed that LDL cholesterol blood 1.81mmol/l (70mg/dl) it is necessary to hold down below. According to Swedish researcher Uffe Ravnskov, this is achieved, the majority of the European-American adults must use the star chin, as for amount used you say that it is above present 8 times.

　If such high dosage is used, when heart failure and myalgra and striated muscle denaturation (the disease where muscle organization is destroyed), nervous obstacle and the cancer (the cancer) etc it means that the side effect increases, as for Ravnskov insistence. In addition, with clinical test it points out also the point where report of the point and the side effect where decrease of mortality rate is not recognized making use of the high dosage star chin is insufficient.

　Vis-a-vis this, the American heart disease academic society (ACC) chairman Steven E. as for Nissen doctor, as for the high dosage star chin when it is safe, you refute from front. There is no data which has persuasive power concerning each side effect, you say that the effect which exceeds risk many with large-scale clinical test is shown. The american University of California Los Angeles (UCLA) heart study professor Gregg C. also Fonarow doctor agrees to this, Ranvskov pick up only the profitable research result to your own insistence, point out that the research which shows the effect of the star chin is overlooked.

　But, in prevention intended star chin use opposes to the last the attitude which Canada which is 1 people of the latest dissertation author, Colombian University pharmacy section emeritus professor British Morley C. Sutter doctor assume, that other than the liver and the muscle there is also a possibility brain function being damaged, depending upon the star chin. The star chin most is the medicine which is sold in the world, because of commercial interests and Sutter doctor has criticized the fact that danger is ignored.