Saturday, September 1, 2007

In ACE obstruction medicine of step-down medicine lung cancer (cancer) reduction effect

In ACE obstruction medicine of step-down medicine lung cancer (cancer) reduction effect


 The angiotensin conversion enzyme which is used for the remedy of the hypertension widely (ACE) in the obstruction medicine, the lung cancer (the cancer) having the effect which makes reduce was shown in research of the mouse. Also research with the person is planned soon and the curative effect whose if harmful characteristic is little becomes profitable and others [ru] thing, it means to bring new desire in the lung cancer remedy whose survival ratio is low.

 The ACE obstruction medicine shows the step-down effect by the fact that formation of the angiotensin Ⅱ where becomes also cause of boosting is obstructed, but the angiotensin which possesses blood vessel expansion action simultaneously - (1-7) with the endogenous peptide which is called (the hormone) it has the function which it increases.

 According to the research which is reported to the medical magazine “Cancer Research” March 15th number, the research team of the American [ueikuhuoresuto] Wake Forest university medical department pays attention to emergence ratio of the lung cancer being low in the hypertension patient who uses the ACE obstruction medicine. Furthermore the result which is researched in detail, the angiotensin - (1-7) [shikurookishigenaze] which is the enzyme which urges the growth of the cell (cox-2) the fact that it is the action which is made to decrease was pinpointed.

 The same university Patricia E. Gallagher transplanted the cancer cell which was picked from the patient of 58 years old to the mouse of 2~4 age in weeks, grew the tumor 32 days. Half the angiotensin of the mouse - (1-7) in order 28 days, to become density in the same blood as the person who receives ACE obstruction medicine remedy, it injected, prescribed the physiological brine to the remaining mouse. The result of dissection after the ending, the angiotensin - (1-7) with the dosage group cox-2 density decreases significantly, as for the tumor of the physiological brine dosage group says the tumor 30% vis-a-vis having reduced, that it grew in 2.5 times that before the dealing with. The angiotensin - (1-7) the poisonous side effect was not seen in the mouse which is prescribed, weight and heart rate, change was not seen even in the blood pressure.

 Concerning dosage and remedy period furthermore it is necessary to repeat research, but that if you can obtain the satisfactory result in research with the person who is started soon, it probably reaches the point where this kind of medicine carries out important role in lung cancer remedy, Gallagher has expressed. With the combined use with the remedy of other things, be able to expect also the possibility where it can decrease the chemotherapy which has the side effect, even if, it is thought even with the small effect that it becomes big help, for the patient. Furthermore another specialist, utilizing the substance of organism origin, has expressed that it is something which shows the possibility of creating the new remedy.

 The american cancer association (ACS) according to, the lung cancer both the man and woman rather than at 1st rank of cause of the death with the cancer, the colon (the colon) adjusting the cancer, the breast cancer and the prostate cancer many Americans has died with the lung cancer. In 10 people 6 people from diagnosis to die within 1 years, as for 5 year survival ratio only 14%. The number of death in the United States people is presumed the annual 170,000 person.

Stop Smoking and Artery Becomes Younger

If it stops smoking, the artery becomes younger


 The artery which is hardened with smoking, gradually recovering flexibility by the fact that it stops smoking was shown in the Irish research. So far, when the artery one becomes time hard, it assumed that it does not return to the origin. It returns to a state where the artery is normal until, because for a while period is required, if it stops smoking, you say that quicker one is good. Hardening the artery comes and rise of the blood pressure and, is connected to the risk increase of heart blood vessel obstacle such as the heart seizure and stroke.

 But Azra Mahmud of Dublin university [toriniteikaretsuji] which continues research concerning the change of the blood vessel with smoking, as for the latest research which is reported with the medical magazine “Hypertension” March edition, the hypertension those which deal with 554 people remedy has not been received. 268 people there is no smoking experience, 150 people the smoker and 136 people were the original smoker, as for the inside 22 people of the original smoker stopping smoking, under 1 years, as for 40 people 1~10 year, as for 40 people were 10 years or more.

 The result of research, being in direct proportion in length of the period when it elapses from prohibition of smoking it became clear for flexibility of the blood vessel to have recovered. When hardness of the artery is appraised with the method of being called “artery wave analysis”, after the smoker and stopping smoking, in it could recognize significant arteriosclerosis each subject under 1 years. Those where you could see big recovery were the subject who 10 years or more elapses from prohibition of smoking. Mahmud, if smoking period excels, have assumed that with the expectation where also the period when it requires for functional recovery is long, furthermore it is necessary to repeat verification.

 As for arteriosclerosis while the person who is thought the thing which is not improved is many, as for the latest result when it is interesting from scientific viewpoint, the American Jones [hopukinsu] university (Baltimore) as for Roger Blumenthal doctor appraisal. It points out also the possibility where it can recognize similar improvement dangerous factor of other heart blood vessel type such as diabetes and hypertension (the risk factor) concerning.

 In another research by the team of the American Michigan University medical department, aging of the skin with smoking was shown, like inside the arm reaching to the part where the sunlight does not hit. Yolanda R which leads research. according to Helfrich doctor, you say that it was found that it is correlation in the number of smoking of the result and 1 days which compare the photograph of the skin of the armpit concerning 77 people who include the long-term smoker and the non smoker boxes and the number of smoking years and the damage of the skin. This knowledge was published to the medical magazine “Archives of Dermatology” March edition.

Medical Therapy is Effective to the Heart Disease

With also only medicine medical therapy is effective to the heart disease which it stabilizes


 If it does centralized medicine medical therapy vis-a-vis the heart disease which it stabilizes, blood vessel formation technique as the case where it does it made clear by the research whose it is new to be able to see the same effect. As for this knowledge, besides the fact that around ahead the American heart academic society which is held in New Orleans (ACC) it was announced with annual meeting, the schedule which is published to also the American medical magazine “New England Journal of Medicine” April 12th number.

 So far, that it is necessary either of heart bypass technique that it was thought in the chronic heart diseased patient whether blood vessel formation technique. William E of American buffalo university medical living thing medical science department professor. according to Boden doctor, blood vessel formation technique and as for 3/4 of the patients who receive [sutento] detention, you say in the United States that it is the heart diseased patient who is stabilized. When in the latest research which is called COURAGE test, it keeps the improvement of reaching suitable medicine medical therapy and life habit in parallel, when blood vessel formation technique and medicine medical therapy is jointly used and without being difference in the effect was ascertained.

 In the latest research, it is stable, but 2,300 patients who have the remarkable heart disease, was allotted to the combined use medical therapy group of the medicine medical therapy independent group and the medicine and blood vessel formation technique randomly. 94% of the combined use groups received one [sutento] detention at least. During pursuit period of 2~7 year, as for the number of occurrences of the death and the heart seizure, with the blood vessel formation technique group 211 (19%) vis-a-vis being with the medicine medical therapy independent group 202 (18.5%). In addition, stroke or acutely crown syndrome (ACS) with significant difference was not seen even with hospitalization and the heart seizure independent comparison.

 Opinion is expressed that from the result, Boden the first line (first executes medicine medical therapy in the heart diseased patient who is stabilized) should remedy. But there are no times when the number of executions of blood vessel formation technique decreases according to Boden, with this, you say that the timing which is executed just becomes slow. However medicine medical therapy is useful ones as an early remedy strategy, we should consider, as those which are inferior unless, the same person has expressed.

 Listing the point and the like where medicine liquation [sutento] is not used in the latest research, you criticize [sutentomeka] and the like, but as for Boden, as for the basis that medicine liquation [sutento] [beametarusutento] compared to is superior vis-a-vis this, in regard to mortality rate and the heart seizure you have refuted that it is not.

 Another specialist the effect due to decreasing dangerous factor substantially with medicine medical therapy has recognized, concerning the patient who is stabilized medicine medical therapy is done first, blood vessel formation technique leaves for the patient who has continuous condition, it should, you have expressed that is.