The reaction of the doctors is calm in heart diseased risk of the diabetes medicine
The diabetes remedy Avandia which is used widely as an insulin resistant improvement medicine (general name: Although in the news that, the medical specialists have shown anxiety, in rosiglitazone, & the Japanese country not yet approval) makes heart seizure risk increase, the reaction which settles generally is shown. But this knowledge, those which are published to the American medical magazine “New England Journal of Medicine” June 14th number, the importance with respect to public health the empty same magazine published on May 21st.
The american diabetes association (ADA) the Sue Kirkman doctors specialist become in panic, vis-a-vis the patient, consulting the family doctor, judges, whether or not risk exceeds the profit, that the medicine is not discontinued selfishly, has advised. The discourse that was published to the English medical magazine “Lancet” May 26th number, it should examine calmly, concerning the safety of Avandia.
The american food medical supply bureau (FDA) the latest knowledge was received, warning regarding the safety of Avandia was sent, but concerning the alarm display to the label you waived furthermore examination as necessity. According to AP communication, the result which supports the latest knowledge even in the spare research which FDA executes individually is shown, the FDA inquiry members are warning which is strongest concerning Avandia several months ago, Charles Grassley Senator (the Republican Party, Iowa state) pointing out that indication of “black box warning” is advised. As for FDA although indication Grassley was recognized, there is also a data which is contrary, you have expressed that it is in the midst of examining.
As for executing the latest research Steven E of the American Cleveland clinic. Nissen doctor and Kathy Wolski. Nissen doctor past as Avandia besides the fact that the heart diseased risk by the medicine muraglitazar of the same class was made clear, assuming that the arthritis remedy (the COX-2 obstruction medicine) Vioxx makes increase the heart seizure and stroke risk to 2004, has driven to the sale discontinuance. In the latest research, as for the patient who uses result and Avandia which are appraised the patient who uses Andiva concerning 42 research which compare with the patient who has not been used heart seizure risk 43% is high, calls the death risk due to the heart blood vessel disease that 64% high thing was ascertained.
The production original [gurakuso] [sumisukurain] corporation of Avandia when it is based on basis and the procedure where the latest research is imperfect is strong refutation. Avandia is used 2,000,000 person or more in the world since approving 1999, as 2 type diabetes medicines, annual 3,200,000,000 dollar (approximately 3,800 hundred million Yen) is a sale. You say that from the fact that it is effective to the fundamental problem of the diabetes, insulin resistance, there is a possibility in the future widely of keeping being used.
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Showing posts with label heart disease risk. Show all posts
Showing posts with label heart disease risk. Show all posts
Wednesday, August 29, 2007
Heart diseased death risk redoubles even with pre- diabetes
Heart diseased death risk redoubles even with pre- diabetes
There just is an extremely early sign of diabetes the death risk due to the heart disease increasing, was shown in the Australian research. Still, it is not diagnosed diabetes and the [te], the person where the complication is exposed dangerously large number means to exist.
In the United States approximately 2,000 ten thousand people have contracted a disease in 2 type diabetes, you say that 6,000,000 person does not become aware in the. 5,600 ten thousand people or more “pre- diabetes (pre-diabetes: The symptom before the diabetes)” with there is a stage which is called, healthy state and the resistance sugar talent abnormality which hits to the center of diabetes (IGT) it has. When 2 type diabetes do not produce the insulin where the body is sufficient, or or when the cell has not reacted to the insulin, this state continues, obstacle happens even to the eye, the kidney, the nerve and the heart. Diabetes is well known heart blood vessel diseased risk and as for early making death risk increase, but relationship between minor blood glucose value rise and heart blood vessel diseased risk was not made so far clear.
As for the latest research which is reported with the American medical magazine “Circulation” June 19th number, the international diabetes laboratory (Melbourne) those by Elizabeth Bar. As for the research group, the Australian “diabetes, obesity and life habit research (AusDiab)” 10,429 person who participated 5 annual pursuit. Oral resistance sugar talent test of the full participant was executed when starting the test, cholesterol value, triglyceride (TG) value was measured. 5 years later, the person of diabetes 2.6 times that of the person where the risk which dies with the heart disease is healthy, the person who the hungry time is abnormal in blood glucose value (makes “pre- diabetes”) with to be 2.5 times, the person who is diabetes and pre- diabetes 2/3 of the whole death in the heart disease had occupied.
The specialists interpret this knowledge as quite the important alarm bell. Being something where the latest research furthermore supports the past research result strongly, you insert power above so far in management of dangerous factor of the blood vessel disease, the opinion that and, simply the person just of resistance sugar talent abnormality, it is necessary to promote motion and appropriate dietary life it is necessary to recognize the importance of diabetes as a dangerous factor more strongly, and so on opinion is put out.
But, how it remedies pre- diabetes, the point in addition whether or not it should remedy of, has not become clear. As for the latest research because it is not something which pays attention to remedy, at least, there are times when it returns to the same as the person whose heart diseased risk of the pre- diabetes patient is healthy from this research, whether or not is, there is also the opinion that it is not understood.
There just is an extremely early sign of diabetes the death risk due to the heart disease increasing, was shown in the Australian research. Still, it is not diagnosed diabetes and the [te], the person where the complication is exposed dangerously large number means to exist.
In the United States approximately 2,000 ten thousand people have contracted a disease in 2 type diabetes, you say that 6,000,000 person does not become aware in the. 5,600 ten thousand people or more “pre- diabetes (pre-diabetes: The symptom before the diabetes)” with there is a stage which is called, healthy state and the resistance sugar talent abnormality which hits to the center of diabetes (IGT) it has. When 2 type diabetes do not produce the insulin where the body is sufficient, or or when the cell has not reacted to the insulin, this state continues, obstacle happens even to the eye, the kidney, the nerve and the heart. Diabetes is well known heart blood vessel diseased risk and as for early making death risk increase, but relationship between minor blood glucose value rise and heart blood vessel diseased risk was not made so far clear.
As for the latest research which is reported with the American medical magazine “Circulation” June 19th number, the international diabetes laboratory (Melbourne) those by Elizabeth Bar. As for the research group, the Australian “diabetes, obesity and life habit research (AusDiab)” 10,429 person who participated 5 annual pursuit. Oral resistance sugar talent test of the full participant was executed when starting the test, cholesterol value, triglyceride (TG) value was measured. 5 years later, the person of diabetes 2.6 times that of the person where the risk which dies with the heart disease is healthy, the person who the hungry time is abnormal in blood glucose value (makes “pre- diabetes”) with to be 2.5 times, the person who is diabetes and pre- diabetes 2/3 of the whole death in the heart disease had occupied.
The specialists interpret this knowledge as quite the important alarm bell. Being something where the latest research furthermore supports the past research result strongly, you insert power above so far in management of dangerous factor of the blood vessel disease, the opinion that and, simply the person just of resistance sugar talent abnormality, it is necessary to promote motion and appropriate dietary life it is necessary to recognize the importance of diabetes as a dangerous factor more strongly, and so on opinion is put out.
But, how it remedies pre- diabetes, the point in addition whether or not it should remedy of, has not become clear. As for the latest research because it is not something which pays attention to remedy, at least, there are times when it returns to the same as the person whose heart diseased risk of the pre- diabetes patient is healthy from this research, whether or not is, there is also the opinion that it is not understood.
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