The reaction of the doctors is calm in heart diseased risk of the diabetes medicine

The reaction of the doctors is calm in heart diseased risk of the diabetes medicine


　The diabetes remedy Avandia which is used widely as an insulin resistant improvement medicine (general name: Although in the news that, the medical specialists have shown anxiety, in rosiglitazone, & the Japanese country not yet approval) makes heart seizure risk increase, the reaction which settles generally is shown. But this knowledge, those which are published to the American medical magazine “New England Journal of Medicine” June 14th number, the importance with respect to public health the empty same magazine published on May 21st.

　The american diabetes association (ADA) the Sue Kirkman doctors specialist become in panic, vis-a-vis the patient, consulting the family doctor, judges, whether or not risk exceeds the profit, that the medicine is not discontinued selfishly, has advised. The discourse that was published to the English medical magazine “Lancet” May 26th number, it should examine calmly, concerning the safety of Avandia.

The american food medical supply bureau (FDA) the latest knowledge was received, warning regarding the safety of Avandia was sent, but concerning the alarm display to the label you waived furthermore examination as necessity. According to AP communication, the result which supports the latest knowledge even in the spare research which FDA executes individually is shown, the FDA inquiry members are warning which is strongest concerning Avandia several months ago, Charles Grassley Senator (the Republican Party, Iowa state) pointing out that indication of “black box warning” is advised. As for FDA although indication Grassley was recognized, there is also a data which is contrary, you have expressed that it is in the midst of examining.

　As for executing the latest research Steven E of the American Cleveland clinic. Nissen doctor and Kathy Wolski. Nissen doctor past as Avandia besides the fact that the heart diseased risk by the medicine muraglitazar of the same class was made clear, assuming that the arthritis remedy (the COX-2 obstruction medicine) Vioxx makes increase the heart seizure and stroke risk to 2004, has driven to the sale discontinuance. In the latest research, as for the patient who uses result and Avandia which are appraised the patient who uses Andiva concerning 42 research which compare with the patient who has not been used heart seizure risk 43% is high, calls the death risk due to the heart blood vessel disease that 64% high thing was ascertained.

　The production original [gurakuso] [sumisukurain] corporation of Avandia when it is based on basis and the procedure where the latest research is imperfect is strong refutation. Avandia is used 2,000,000 person or more in the world since approving 1999, as 2 type diabetes medicines, annual 3,200,000,000 dollar (approximately 3,800 hundred million Yen) is a sale. You say that from the fact that it is effective to the fundamental problem of the diabetes, insulin resistance, there is a possibility in the future widely of keeping being used.

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