The cancer (the cancer) the control protein (the protein) prevents also aging

The cancer (the cancer) the control protein (the protein) prevents also aging


　In p53 and the cell adjustment factor Arf which are known the cancer (the cancer) the control protein (the protein) as, having the function which can delay aging the Spanish national cancer research center (Madrid) was shown in research Manuel Serrano, was published to the English scientific magazine “Nature” July 19th number.

　For the cancer researcher, it is the substance to which the p53 protein adapts and is deep. p53 is made with the organism, there is the function which removes the cell where the risk which is converted malignantly is high, Arf assumes that that function is helped by informing about the cell which it should remove in p53. Serrano, in order to reveal p53 and Arf excessively, the gene the mouse which was operated while many years use for research, life of this mouse became aware in being longer than the other mouse.

　In the latest research, the cell which was picked from the p53/Arf excessive production mouse in detail examination. It could recognize the delay of the result and aging which inspected the aging marker, the cancer depression effect was considered and furthermore it became clear to be able to see the extension of life.

　As for Serrano, as for aging being controlled by p53 and Arf, when the cancer is controlled, opinion is expressed that completely it is the same reason. Aging defect of the cell accumulating, is thought that it occurs, but when as for p53 and Arf in a manner of speaking being something which bears “the quality control” of the cell, about the mouse whose p53 is many the cell is harshly managed, to become also aging it is loose difficult in the cancer, Serrano calls.

　The american stand age increase laboratory (NAI) according to Felipe Sierra, when life gets near to end in any Mammalia, emergence ratio of the cancer rises suddenly, but you say that you can explain the reason with p53. Nearly 80 years in case of the person who lives, it is necessary to prevent the cancer just that over the long period of time, p53 has helped that. While being young, p53/Arf has prevented the cancer, but when you grow older, when the effect becomes weak, the same person thinks. Everyone having close relationship to aging and the cancer as for felt, but as for the latest research you say that it is something which shows the basis.

　But, those like the Hurou immortal medicine do not have to be expected directly. The numerous chemical substance which makes p53 of in vivo increase it is developed by the major medicine manufacture company, but still at extremely early test stage, as for adjusting the action of p53 precisely unless it is easy, Serrano indication. Sierra with the same opinion, to the last fundamental mechanism just became clear, as for those where the operation is discussed with timewise prematureness, “young, the spring” has expressed that immediately there is no there.