Showing posts with label cancer. Show all posts
Showing posts with label cancer. Show all posts

Saturday, September 1, 2007

In ACE obstruction medicine of step-down medicine lung cancer (cancer) reduction effect

In ACE obstruction medicine of step-down medicine lung cancer (cancer) reduction effect


 The angiotensin conversion enzyme which is used for the remedy of the hypertension widely (ACE) in the obstruction medicine, the lung cancer (the cancer) having the effect which makes reduce was shown in research of the mouse. Also research with the person is planned soon and the curative effect whose if harmful characteristic is little becomes profitable and others [ru] thing, it means to bring new desire in the lung cancer remedy whose survival ratio is low.

 The ACE obstruction medicine shows the step-down effect by the fact that formation of the angiotensin Ⅱ where becomes also cause of boosting is obstructed, but the angiotensin which possesses blood vessel expansion action simultaneously - (1-7) with the endogenous peptide which is called (the hormone) it has the function which it increases.

 According to the research which is reported to the medical magazine “Cancer Research” March 15th number, the research team of the American [ueikuhuoresuto] Wake Forest university medical department pays attention to emergence ratio of the lung cancer being low in the hypertension patient who uses the ACE obstruction medicine. Furthermore the result which is researched in detail, the angiotensin - (1-7) [shikurookishigenaze] which is the enzyme which urges the growth of the cell (cox-2) the fact that it is the action which is made to decrease was pinpointed.

 The same university Patricia E. Gallagher transplanted the cancer cell which was picked from the patient of 58 years old to the mouse of 2~4 age in weeks, grew the tumor 32 days. Half the angiotensin of the mouse - (1-7) in order 28 days, to become density in the same blood as the person who receives ACE obstruction medicine remedy, it injected, prescribed the physiological brine to the remaining mouse. The result of dissection after the ending, the angiotensin - (1-7) with the dosage group cox-2 density decreases significantly, as for the tumor of the physiological brine dosage group says the tumor 30% vis-a-vis having reduced, that it grew in 2.5 times that before the dealing with. The angiotensin - (1-7) the poisonous side effect was not seen in the mouse which is prescribed, weight and heart rate, change was not seen even in the blood pressure.

 Concerning dosage and remedy period furthermore it is necessary to repeat research, but that if you can obtain the satisfactory result in research with the person who is started soon, it probably reaches the point where this kind of medicine carries out important role in lung cancer remedy, Gallagher has expressed. With the combined use with the remedy of other things, be able to expect also the possibility where it can decrease the chemotherapy which has the side effect, even if, it is thought even with the small effect that it becomes big help, for the patient. Furthermore another specialist, utilizing the substance of organism origin, has expressed that it is something which shows the possibility of creating the new remedy.

 The american cancer association (ACS) according to, the lung cancer both the man and woman rather than at 1st rank of cause of the death with the cancer, the colon (the colon) adjusting the cancer, the breast cancer and the prostate cancer many Americans has died with the lung cancer. In 10 people 6 people from diagnosis to die within 1 years, as for 5 year survival ratio only 14%. The number of death in the United States people is presumed the annual 170,000 person.

Thursday, August 30, 2007

The vegetable and the fruit repulse the cancer (the cancer)

The vegetable and the fruit repulse the cancer (the cancer)


 By the intake of the vegetable and the fruit, the various cancer (the cancer) three research which show the fact that risk decreases, the American cancer academic society which is held in Los Angeles (AACR) were reported with annual meeting.

 The american stand cancer laboratory (NCI) as for the research by Neal Freedman, targeting adult 490,802, the intake quantity of the fruit and the vegetable and those which compare the rate of occurrence of the head neck cancer. The fact that it was diagnosed the head neck cancer in 5 years was 787. Smoking and alcoholic intake dangerous factor (the risk factor) after the adjusting, concerning 1 day 1,000 caloric intake such as fruit or as for the person who 6 plates takes in the vegetable, head neck cancer risk 29% was low only 1.5 plates in comparison with the person who is not taken in, 1 plates just adds even could recognize 6% risk decrease. Independently you say that you could see the preventive effect where the vegetable is higher than the fruit.

 The american University of California Los Angeles (UCLA) the research group the broccoli and the soybean (the soy bean) the protein (the protein) due to reported the research result at laboratory level concerning the mechanism of the preventive effect for the breast cancer and the ovarian cancer. When the broccoli is digested, when [jiindorirumetan] (DIM) with the substance which is said is digested, the soybean, the substance, [genisutein] is formed. This time, these substances, operated the maneuverability of the cell of the breast cancer and the ovarian cancer, it was found that spread of the cancer is controlled. But, in the soybean the estrogen way because there is action, the person who has the cancer which is promoted by the estrogen says that note is necessary.

 The research group of American Hawaiian cancer research center targeting 180,000 3,518 people of California and the Hawaiian residence compared the intake quantity and cancer risk. As for, the onion and the apple, the substance which very is included in type, the kale and the broccoli etc. Besides the fact that with the person where the intake quantity is highest cancer risk 23% low thing it was understood, with the smoker furthermore the effect is large, as for the person where the intake quantity is high cancer risk was ascertained 59% low thing.

 When you can say, that it is best to cancer prevention to take in the plant characteristic food of various types from 3 research above, the American cancer research association (AICR) Melanie Polk has expressed. Besides the fact that it goes to the direct sales depot of the farmer, spends time at the foodstuff store and closely examines the vegetable, when also the device such that the cooking method which can eat the vegetable tastily is found it is necessary Polk calls.

Wednesday, August 29, 2007

Mismatch of the opinion that the doctor the cancer (the cancer) raises the death risk of the patient

Mismatch of the opinion that the doctor the cancer (the cancer) raises the death risk of the patient


 When it has the opinion which differs from charge medicine the advance cancer (the cancer) the patient concerning itself body state and nutrition state, it was shown in the research death risk becoming high by Ian Schnadig doctors of the American Oregon Health Sciences University cancer laboratory, the American cancer remedy academic society which is held in Chicago (ASCO) it was announced with annual meeting.

 In the latest research, PS of patient (performance status; When the index which shows the systemic health state of the patient and the ability to operate every day) appraisal does not match the doctor, death risk increased 11%, when appraisal of nutrition state does not agree, you say that 38% increasing was ascertained. If appraisal agrees, is not something where, lifetime extends, but when it is thought that lack of communication has brought the deterioration of convalescence, the specialist points out.

 At the time of this research, the team of the same university the advance colon (the colon) obtaining the cooperation of rectum cancer and 1,636 lung cancer patients, executed the pursuit of 7 years. The doctor and the patient were recognized respectively, PS appraisal of 2 types and nutrition state appraisal of 1 types the result of doing, respectively 56.6%, 67.1% and 58%, in each case doing the appraisal where the patient above the half differs from the doctor.

 As a whole, the doctor there was a tendency which acquires the appraisal which is higher than the patient. In addition, with the patient whom it becomes impossible to work before the especially retirement age, the mismatch with the doctor is easy occurring concerning the appraisal regarding work it was recognized. Educational background as for the person under high soldier/finishing besides the fact that you could see the mismatch with the doctor more than the person who has the educational background above the university, frequently the [u] the person who appeals state mismatch ratio was high.

 Schnadig has expressed that it is important to keep agreeing the appraisal that the doctor and the patient, concerning PS and nutrition state. As a method for that, when periodically vital sign of the blood pressure and heart rate etc (life sign) it measures, in the same way, in every fixed period you take the data from the patient and you can think that among other things the appraisal value which is used with thing and the clinical test where makes submit to the doctor is adopted. But, when the doctor should hear the story of the patient better, as simpler solution than that, there is also opinion. “The patient has wished to know his own state”, that the specialist points out.

The cancer (the cancer) the control protein (the protein) prevents also aging

The cancer (the cancer) the control protein (the protein) prevents also aging


 In p53 and the cell adjustment factor Arf which are known the cancer (the cancer) the control protein (the protein) as, having the function which can delay aging the Spanish national cancer research center (Madrid) was shown in research Manuel Serrano, was published to the English scientific magazine “Nature” July 19th number.

 For the cancer researcher, it is the substance to which the p53 protein adapts and is deep. p53 is made with the organism, there is the function which removes the cell where the risk which is converted malignantly is high, Arf assumes that that function is helped by informing about the cell which it should remove in p53. Serrano, in order to reveal p53 and Arf excessively, the gene the mouse which was operated while many years use for research, life of this mouse became aware in being longer than the other mouse.

 In the latest research, the cell which was picked from the p53/Arf excessive production mouse in detail examination. It could recognize the delay of the result and aging which inspected the aging marker, the cancer depression effect was considered and furthermore it became clear to be able to see the extension of life.

 As for Serrano, as for aging being controlled by p53 and Arf, when the cancer is controlled, opinion is expressed that completely it is the same reason. Aging defect of the cell accumulating, is thought that it occurs, but when as for p53 and Arf in a manner of speaking being something which bears “the quality control” of the cell, about the mouse whose p53 is many the cell is harshly managed, to become also aging it is loose difficult in the cancer, Serrano calls.

 The american stand age increase laboratory (NAI) according to Felipe Sierra, when life gets near to end in any Mammalia, emergence ratio of the cancer rises suddenly, but you say that you can explain the reason with p53. Nearly 80 years in case of the person who lives, it is necessary to prevent the cancer just that over the long period of time, p53 has helped that. While being young, p53/Arf has prevented the cancer, but when you grow older, when the effect becomes weak, the same person thinks. Everyone having close relationship to aging and the cancer as for felt, but as for the latest research you say that it is something which shows the basis.

 But, those like the Hurou immortal medicine do not have to be expected directly. The numerous chemical substance which makes p53 of in vivo increase it is developed by the major medicine manufacture company, but still at extremely early test stage, as for adjusting the action of p53 precisely unless it is easy, Serrano indication. Sierra with the same opinion, to the last fundamental mechanism just became clear, as for those where the operation is discussed with timewise prematureness, “young, the spring” has expressed that immediately there is no there.

The cancer (the cancer) the new inspection method which early makes diagnosis possible

The cancer (the cancer) the new inspection method which early makes diagnosis possible


 The cancer of early stage (the cancer) the possibility where it can inspect safely and accurately was shown in small-scale extra research, was reported with the medical magazine “Clinical Cancer Research” August 1st number. The cell of the duodenum which was picked due to endoscope biopsy, when is inspected making use of light scattering, with when there are no with times when there is cancer, you say that the scattering effect which is different is shown.

 The american [nosuuesutan] university which leads research (Illinois state [ebansuton]) as for Vadim Backman, the patient who has the family history of the cancer due to this method, risk you have expressed that there is also a possibility of reaching the point where dying every year it can receive inspection. cancer action network (PanCAN) also Julie Fleshman, while we assuming, that furthermore detailed research is necessary, this inspection has shown expectation in the possibility of becoming the important tool for the patient.

 The large star of the opera boundary, [ruchiano] [pavuarotsutei] presently as for the cancer which is known by also the fact that the fighting illness it has done, when condition appears, having already spread to the other internal organs is many, as for 5 year survival ratio under 5%, in 3 people as for 1 people from diagnosis you die it is the fearful disease within 1 years. With scan technology in addition to discovering the 膵 cancer of early stage, biopsy and the stab (the plug and so on to do) in the inspection whose invasive characteristic is high the risk which the complication does to come heavily seriously is also 20% or more, it assumes that they are the internal organs whose treatment quite is difficult.

 The research team had already pinpointed the fact that early of the colon which it adjoins from the inspection body which was picked in the rectum biopsy making use of the technology due to optical spread, the cancer can be inspected. From this, the pancreas nearly it is located immediately, pays attention to the easy duodenum of biopsy picking. Organization of the duodenum was extracted from 51 subjects, due to endoscope biopsy. Portion of the subject is the patient who already has the cancer of various illness periods. In the cell where it picked, the result of carrying out the optical spread inspection of 2 types, early and 100% it was possible to inspect the cancer of the latter term. There was a false positivity of several examples, but you do not know whether this being the mere mistake, whether in the future that subject the cancer it is something which shows the fact that the risk which emerges is high.

 As for Backman, as for this inspection it has emphasized that it is something which deals with the person who to the last has the family history of the cancer. [manmoguramu] of the woman (breast X-ray inspection) and PSA of the man (the prostate unique antigen) in inspection the way when still it is distant, Fleshman calls the actualization of the cancer inspection which can be executed widely generally. The team Backman has tackled the large-scale test which already deals with 200 people or more concerning this light scattering inspection. Besides the fact that the cancer and when discriminating the other benign diseases, usefulness are examined, you say that the person who has the family history it is the schedule which also comparison of the person who is not does. Fleshman, although big expectation is moved aside to possibility of this inspection, furthermore points out the point where huge cost is necessary to cancer research.