The reaction of the doctors is calm in heart diseased risk of the diabetes medicine

The reaction of the doctors is calm in heart diseased risk of the diabetes medicine


　The diabetes remedy Avandia which is used widely as an insulin resistant improvement medicine (general name: Although in the news that, the medical specialists have shown anxiety, in rosiglitazone, & the Japanese country not yet approval) makes heart seizure risk increase, the reaction which settles generally is shown. But this knowledge, those which are published to the American medical magazine “New England Journal of Medicine” June 14th number, the importance with respect to public health the empty same magazine published on May 21st.

　The american diabetes association (ADA) the Sue Kirkman doctors specialist become in panic, vis-a-vis the patient, consulting the family doctor, judges, whether or not risk exceeds the profit, that the medicine is not discontinued selfishly, has advised. The discourse that was published to the English medical magazine “Lancet” May 26th number, it should examine calmly, concerning the safety of Avandia.

The american food medical supply bureau (FDA) the latest knowledge was received, warning regarding the safety of Avandia was sent, but concerning the alarm display to the label you waived furthermore examination as necessity. According to AP communication, the result which supports the latest knowledge even in the spare research which FDA executes individually is shown, the FDA inquiry members are warning which is strongest concerning Avandia several months ago, Charles Grassley Senator (the Republican Party, Iowa state) pointing out that indication of “black box warning” is advised. As for FDA although indication Grassley was recognized, there is also a data which is contrary, you have expressed that it is in the midst of examining.

　As for executing the latest research Steven E of the American Cleveland clinic. Nissen doctor and Kathy Wolski. Nissen doctor past as Avandia besides the fact that the heart diseased risk by the medicine muraglitazar of the same class was made clear, assuming that the arthritis remedy (the COX-2 obstruction medicine) Vioxx makes increase the heart seizure and stroke risk to 2004, has driven to the sale discontinuance. In the latest research, as for the patient who uses result and Avandia which are appraised the patient who uses Andiva concerning 42 research which compare with the patient who has not been used heart seizure risk 43% is high, calls the death risk due to the heart blood vessel disease that 64% high thing was ascertained.

　The production original [gurakuso] [sumisukurain] corporation of Avandia when it is based on basis and the procedure where the latest research is imperfect is strong refutation. Avandia is used 2,000,000 person or more in the world since approving 1999, as 2 type diabetes medicines, annual 3,200,000,000 dollar (approximately 3,800 hundred million Yen) is a sale. You say that from the fact that it is effective to the fundamental problem of the diabetes, insulin resistance, there is a possibility in the future widely of keeping being used.

Original

Mismatch of the opinion that the doctor the cancer (the cancer) raises the death risk of the patient

Mismatch of the opinion that the doctor the cancer (the cancer) raises the death risk of the patient


　When it has the opinion which differs from charge medicine the advance cancer (the cancer) the patient concerning itself body state and nutrition state, it was shown in the research death risk becoming high by Ian Schnadig doctors of the American Oregon Health Sciences University cancer laboratory, the American cancer remedy academic society which is held in Chicago (ASCO) it was announced with annual meeting.

　In the latest research, PS of patient (performance status; When the index which shows the systemic health state of the patient and the ability to operate every day) appraisal does not match the doctor, death risk increased 11%, when appraisal of nutrition state does not agree, you say that 38% increasing was ascertained. If appraisal agrees, is not something where, lifetime extends, but when it is thought that lack of communication has brought the deterioration of convalescence, the specialist points out.

　At the time of this research, the team of the same university the advance colon (the colon) obtaining the cooperation of rectum cancer and 1,636 lung cancer patients, executed the pursuit of 7 years. The doctor and the patient were recognized respectively, PS appraisal of 2 types and nutrition state appraisal of 1 types the result of doing, respectively 56.6%, 67.1% and 58%, in each case doing the appraisal where the patient above the half differs from the doctor.

　As a whole, the doctor there was a tendency which acquires the appraisal which is higher than the patient. In addition, with the patient whom it becomes impossible to work before the especially retirement age, the mismatch with the doctor is easy occurring concerning the appraisal regarding work it was recognized. Educational background as for the person under high soldier/finishing besides the fact that you could see the mismatch with the doctor more than the person who has the educational background above the university, frequently the [u] the person who appeals state mismatch ratio was high.

　Schnadig has expressed that it is important to keep agreeing the appraisal that the doctor and the patient, concerning PS and nutrition state. As a method for that, when periodically vital sign of the blood pressure and heart rate etc (life sign) it measures, in the same way, in every fixed period you take the data from the patient and you can think that among other things the appraisal value which is used with thing and the clinical test where makes submit to the doctor is adopted. But, when the doctor should hear the story of the patient better, as simpler solution than that, there is also opinion. “The patient has wished to know his own state”, that the specialist points out.