The cause protein of the Alzheimer's disease (the protein) participates in also glaucoma

The cause protein of the Alzheimer's disease (the protein) participates in also glaucoma


　Old person unevenness (the plaque) the amyloid which is formed - ## (beta) the protein (the protein), the possibility of becoming cause of retina cell death in the glaucoma it was shown in the brain of the Alzheimer's disease patient, “Proceedings of the National Academy of Science (PNAS)” of the American scientific academy issue August 7th was published to online edition (printing edition August 10-16th in the number publication).

　In the latest research, the English London university (UCL) M. as for Francesta Cordeiro doctors, vis-a-vis the rut/rat which in order to emerge, operated glaucoma the amyloid - when the medicine which obstructs the formation route ## is used, the damage of the eye lightened, life of the retina cell extended. When obstruction of formation route was tried with method of several types, when the effect is highest in 1 types among those, jointly uses the method of all type, you say that furthermore you could see the big effect.

　As for this knowledge, there is also a possibility of becoming the key which solves the doubt which has surfaced recently between the ophthalmologists concerning glaucoma remedy. To several years ago, glaucoma is stated when it is something where retina cell death happens with the abnormal rise of eye pressure, the remedy which presently lowers eye pressure mainly is done, but to tell the truth as for eye pressure normally close thing has known above the half of the glaucoma patient. We have assumed that the American ophthalmology academic society (AAO) presently, eye pressure rise it deletes the description which we assume, that it is cause of glaucoma, simply main dangerous factor (the risk factor) is.

　As for Corderio, the amyloid - you observe to ## by the fact that you could see the retina cell death which is similar to glaucoma in the Alzheimer's disease patient. Besides the fact that the amyloid - it could recognize the accumulation ## in the retina cell which becomes extinct, when the amyloid - it adds ## in the retina cell which was cultured cell death being induced it was recognized. When also the possibility where it can remedy the Alzheimer's disease the eye from this research, as the entrance of the body using it is Corderio has expressed.

　The american duke university (North Carolina) Stuart J. McKinnon doctor, method of thinking where there is a root of this research although it makes proper, there is no animal model where eye pressure glaucoma is superior low, in the latest research, pointing out the point which uses the rut/rat model which emerges glaucoma to a high eye pressure. Appraisal has expressed that it should make prudent. In addition, also cause of cell death being unclear, you do not know whether being the difference of the gene, whether it is difference of the sensitivity for eye pressure. But, it is certain, for the road to the new cure where in any case the amyloid - it designates ## as the target to be opened sooner or later when also the possibility of the vaccine actualization which prevents plaque formation it is as for the specialists you express.